Active pharmaceutical ingredients (APIs) exhibiting low aqueous solubility or poor intestinal permeability will be associated with poor or variable drug absorption. Lipid-based drug delivery (LBDD) has emerged as a successful approach to…

You have you missed the most popluar articles of this week? No worries you will find them here. We also include the top phama excipient pages of last month and the most popular posts of the current year. This might give some hints which…

Recent work showed that contrary to conventional wisdom, fine surface engineered excipients outperform their larger counterparts in blends of highly loaded blends of cohesive drug powders in terms of their packing, flowability and tablet…

The aim of the present paper is to study the effect of common excipients on the permeability of atenolol (as drug absorbed mainly by passive diffusion) and rhodamine (as P-Glycoprotein substrate). Apparent permeability was measured by in…

Find a summary of the most popular posts on excipients and formulation of the last week: Top posts of the week #1 Amorphous Solid Dispersions - Ask a specialist #2 Viscosity of API/fatty acid suspensions: Pitfalls during analysis #3…

Brussels, 02 June 2020 EXCiPACT asbl is pleased to announce details of their free-to-attend seminar to be held in Frankfurt at DQS offices on Wednesday, 25 November 2020 with the following program: 09.45h Registration/Coffee 10.15h…

This study focuses on the fate of excipients contained in topical emulsions once applied on the skin. The aim was thus to develop a methodology to characterize the residue left on the skin shortly after emulsion application. To this end,…

Find a summary of the most popular posts on excipients and formulation of the last week: Top posts of the week #1 Cyclodextrin complexation studies as the first step for repurposing of chlorpromazine #2 Design (QbD) Approach to Match…

The compaction of multiple unit-pellet system (MUPS) tablets poses considerable challenges due to potential compaction-induced damage to the functional polymer coat and segregation of pellets from other excipients during the tableting…