Solidification of carvedilol loaded SMEDDS by swirling fluidized bed pellet coating Self-(micro)emulsifying drug delivery systems (S(M)EDDS) have emerged as effective vehicles for enhancing bioavailability of poorly water soluble drugs,…

Solid dispersions production is one of the substantial approaches for improvement of poor drug solubility. Additionally, supercritical fluid assisted method for preparation of solid dispersions can offer many advantages in comparison to the…

07. June 2018 Wet granulation is mostly used process for manufacturing matrix tablets. Compared to the direct compression method, it allows for a better flow and compressibility properties of compression mixtures.…

24. February 2016 Compression coating technique has been used in formulation of chronotherapeutic drug delivery systems with pulsatile carvedilol release with polyethylene oxide as controlling release agent. FMEA, risk…

Abstract Clobetasol-17-proprionate (CP) is the most potent, highly lipophilic topical corticosteroid, used for the treatment of immune-mediated muco-cutaneous diseases. No commercial preparations are available for oral cavity and galenic…

Abstract The purpose of this study was to investigate improving solubility using hydrophilic/water-soluble polymers as β-Cyclodextrin and Plasdone K-30 in a solid dispersion formulation of Carvedilol a poorly soluble drug. The…

Abstract Back ground: Orally administered medication solubility is a key concern for the pharmaceutical business; about 35-40% of newly introduced pharmaceuticals have less aqueous solubility, resulting in deprived dissolution and limited…