The treatment of several ocular inflammatory conditions affecting different areas of the ocular globe involves the administration of topical ophthalmic formulations containing corticosteroids. This research was aimed at evaluating the…

Introduction With target-oriented drug discovery and an increasing focus on specialized medicines, the manufacturing of final drug products is becoming more and more complex. The processing and formulation of active pharmaceutical…

Vulvovaginal candidiasis is a vaginal infection that affects women of reproductive age. Nowadays, the high administration frequency of conventional antifungal formulations, and recurrences negatively impact patients’ well-being. In this…

Incorporation of an emulsion onto a gel base develops a drug delivery system with improved characteristics, known as emulgel, that can envelop both hydrophilic and lipophilic molecules, and therefore increase stability and penetration of…

Chronic wounds affect millions of people globally. This number is set to rise with the increasing incidence of antimicrobial-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA), which impair the…

Ophthalmic drugs are delivered to the eye to treat chronic diseases such as dry eye and acute conditions such as inflammation and infections. The market for drugs administered to the eye is growing, in large part, due to our aging…

Nepafenac is a highly effective NSAID used for treating postoperative ocular inflammation and pain after cataract surgery and its advantage over conventional topical NSAIDs has been proved many times. However, Nevanac® is a suspension eye…

Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants are drugs that can inhibit the body’s immune response. Considering drug side effects such as hepatorenal toxicity and the unique structure of the eye,…

Successful ophthalmic drug formulations rely on the selection of the correct polymer to ensure the desired characteristics such as retention in the eye cavity and solubility. One example of such an excipient is polyvinyl alcohol (PVA) which…