The nano-particulate system for oral delivery faces a big challenge across the gastrointestinal bio-barriers. The aim was to explore the potential applications of bile acid transporter mediated the self-assembled hybrid nanoparticles…

The development of drug delivery carriers is often very challenging, due to the physicochemical properties of the drug such as poor solubility, low permeability, and short half-life. Development of colloidal delivery systems has introduced…

Disulfiram (DSF), an FDA-approved anti-alcoholic drug, has recently shown that it possesses anti-cancer effects. However, DSF is hydrophobic in nature with less stability. Therefore, new approaches are required for the effective delivery of…

Many functional substances are hardly dissolved in water or lipid at ambient temperature, which causes some difficulties in product formulation. Therefore, the aim of this research was to develop a novel carrier system by complexing…

Most cancer disease can be treated by the parenteral anticancer delivery method. The intravenous route takes the wholly bioavailable, accurate dose of the drug immediately to the body, but high plasma concentration has some side effects.…

Lipid-based nanocarriers are promising tools to deliver APIs, including peptides, as their nanosize are in favour of transepithelial transport. Solid Lipid Nanoparticles (SLN) are composed of lipids in solid state at room and body…

Starch nanoparticles were prepared from native potato starch using acid hydrolysis and precipitation methods. The acid hydrolysis method yielded high relative crystallinity of starch nanoparticles (SNP-H), while ethanol precipitation…

Nanoparticle-based mucosal drug delivery is a promising method to increase the residence time of a drug in the mucosa. It is known that the stability of polysaccharide-based nanoparticles in aqueous solutions is limited, due to…

In the current study, we developed interpolymer-complex structures composed of hydroxypropyl methylcellulose (HPMC) and chitosan knitted with d-α-tocopherol polyethylene glycol succinate (TPGS) to establish oral nanoparticle delivery…

Antimicrobial resistance is one of the most serious problems that researchers of multiple disciplines are working on. The number of new antibiotics and their targeted structures have continuously decreased emphasizing the demand of…