What is the ExciPerience? - A short summary ExciPerience is the virtual event around every aspect of pharmaceutical excipients. ExciPerience covers all areas from basic or advanced research and formulation to manufacturing and regulatory.…

In the manufacturing of pharmaceutical Oral Solid Dosage (OSD) forms, Particle Size Distribution (PSD) and Tensile Strength (TS) are common in-process tests that are controlled in order to achieve the quality targets of the end-product. The…

In this paper we present a thorough description of the digital twin development for a continuous pharmaceutical powder blending process in accordance with the Process Analytical Technologies (PAT) and Quality by Design (QbD) guidelines. A…

Quercetin (QCT) is an effective antioxidant, antifibrotic and wound healing agent. Silver nanoparticles (AgNPs) are an effective antimicrobial and wound healing agent and considered as gold standard for wound treatment especially diabetic…

Background: The current study sought to formulate a dry powder inhalant (DPI) for pulmonary delivery of lipopolymeric nanoparticles (LPNs) consisting of cisplatin and siRNA for multidrug-resistant lung cancer. siRNA against ABCC3 gene was…

Melt granulation is an interesting alternative technique to produce both, immediate and controlled-release final products using twin-screw extruders. The aim of this current work was to gain a deeper understanding of the granule’s…

This study aimed to design and characterize Tofacitinib (TF)-loaded lyotropic liquid crystalline nanoparticles (TF-LCNP) gel using quality by design-driven approach to enhance the skin delivery of TF. The present work investigated the…

Background: Multiple dosing is required for bosentan in order to achieve steady-state concentration. Hence formulating bosentan controlled release formulation could be an approach to solve this issue. Objective: The objective is to…

Hot-melt extrusion has found extensive application as a feasible pharmaceutical technological option over recent years. HME applications include solubility enhancement, taste masking, and sustained drug release. As bioavailability…