In the present study, the performance of PROSOLV® EASYt ab SP was tested in four DC formulations with different model APIs. Each of the selected APIs presented a particular challenge in terms of producing tablets with suitable hardness,…

Cocrystals can improve drug dissolution by generating supersaturated drug delivery systems. However, supersaturation is a high-energetic state with a tendency to precipitate. Polymers are used as precipitation inhibitors to inhibit…

Stable drug-type tablets and capsules are painful to drink or chew for many pediatric and geriatric patients. Accurate dosing is also an issue for liquid orals (syrup, suspension, emulsion, and so on). Several fast-dissolving drug delivery…

COVID19 has caused a significant socioeconomic burden worldwide. Opioid crisis was further intensified with the increasing number of opioid overdose/misuse related deaths in last two years. Abusers have adopted newer/efficient methods for…

European Food Safety Authority’s (EFSA) updated assessment on the safety of titanium dioxide as a food additive (published in summer 2021) concludes, that concerns about the genotoxicity of TiO2 particles cannot be excluded. As a result,…

The synergistic therapeutic benefits of resveratrol (RES) and piperine (PIP) have been proven for the treatment of various diseases. This study reports, for the first time, spray-drying of hydroxypropyl β-cyclodextrin (HP-β-CD)…

The 12th APV PBP World Meeting took place from 28 – 31 March 2022 in Rotterdam. There was a poster section at the event where really interesting scientific posters were presented. Therefore we asked the presenting scientists if we could…

The present study focuses on the compaction behavior of polymeric excipients during compression in comparison to nonpolymeric excipients and its consequences on commonly used Heckel analysis. Compression analysis at compaction pressures…

Roquette’s plant-based softgel offering is expanding to provide manufacturers with a complete ready-to-use LYCAGEL® Premix. Easy to incorporate into existing gelatin softgel manufacturing processes, LYCAGEL® Premix promises all the benefits…