Current researches in the branch of polymer-mediated transdermal drug delivery systems (DDSs) are one of the most promising approaches as it bypasses the hepatic first-pass metabolism and improves patient compliance. The main barrier to…

Delivery to small intestine is the most sought and favorable approach among the therapeutics delivered by oral route. The significant importance of preferential delivery of drugs to the intestine is the availability of large surface area,…

Gastroretentive drug delivery system (GRDDS) is one of the key research areas in focus due to its ability to improve therapy by increasing residence time of drugs having narrow absorption window, demand residence in stomach due to their…

Over the last decades, systemic drug delivery through oral mucosa has received a great deal of attention. Actually buccal mucosa is an attractive route due to its ease of accessibility, rapid efficacy, smooth and relatively immobile…

Polymers have been an important component in the development of drug delivery systems because of their ability to release active ingredients for a longer period of time without fluctuations in plasma levels. The first polymeric based drug…

In situ film forming systems are an alternative to the conventional dosage forms for topical application, performing superior contact and adhesiveness, with a consequent sustained and efficacious therapy. Propolis (PRP) is an extremely…

Targeted delivery of drugs at appropriate concentrations to ocular tissues is required to avoid wastage. Hence, advanced systems that maximize the release of poorly soluble drugs and deliver them at ocular sites must be designed. Methods:…

Dimenhydrinate is a therapeutic agent used for the treatment of nausea and vomiting. A conventional dose of dimenhydrinate is 50 mg per 8 h. Once-daily controlled release tablets of dimenhydrinate were formulated intended to treat emesis.…

To develop a scalable and efficient process suitable for the continuous manufacturing of poly(lactic-co-glycolic acid) (PLGA) nanoparticles containing ovalbumin as the model protein. PLGA nanoparticles were prepared using a double…

In this study, a novel solubility enhancement excipient (Soluplus®) was investigated to improve the solubility and dissolution rate of Curcumin, a poorly water soluble drug. Methods Various methods were utilized for the fabrication of…