In this webinar Norbert Pöllinger and Tom West presented the unique opportunities offered by the combination of 3D printing and multiparticulates to achieve novel solutions in ODT application. They demonstrated how swallowing issues of high…

Context: Overcoming the intestinal mucosal barrier can be a challenge in drug delivery. Nanoemulsions with negative zeta potentials can effectively permeate the mucus layer, but those with positive zeta potentials are better taken up by…

Nanomedicines based on poly(lactic-co-glycolic acid) (PLGA) carriers offer tremendous opportunities for biomedical research. Although several PLGA-based systems have already been approved by both the Food and Drug Administration (FDA) and…

Achieving the appropriate release kinetics for an active pharmaceutical ingredient (API) is essential to ensure success of the therapeutic. For example, for sustained release formulations, a consistent API dose over a prolonged period…

Abstract: Salinomycin (Sal) is a potent inhibitor with effective anti-breast cancer properties in clinical therapy. The occurrence of various side effect of Sal greatly limits its application. The epidermal growth factor receptor (EGFR)…

This review aims to provide the state of the art on polymeric and lipid nanoparticles, used or suggested to approach pediatric diseases’ problems and needs, and to inspire new researches in this field. Several drugs are currently not…

Inulin is a heterogeneous green polysaccharide obtained from natural sources. It is found in a variety of regularly eaten vegetables, fruits, cereals, and in their roots and rhizomes including onion, leek, wheat, garlic, dahlia, asparagus,…

The utilization of 3DP as manufacturing process might provide some potential benefits for the pharmaceutical industry as well as for patients. In regard to customization and tailoring of pharmaceutical dosage forms, 3DP appears to have a…