Modified- or sustained-release matrices are designed to release a drug slowly over an extended period of time. Formulations must be robust to ensure drug release over time and avoid dose-dumping. Lipid-based matrices are water-insoluble and…

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Aim: The aim of the present work was to fabricate customized tablets of ciprofloxacin hydrochloride through 3D printing for optimized dosing.  Materials & methods: A hot melt extrusion technique was employed to produce polyvinyl…

Thesis by Jeremiah Kelleher, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, The University of Dublin The thesis has focused on the use of continuous manufacturing techniques to produce fixed dose combination…

Although not readily accessible yet to many community and hospital pharmacists, fuse deposition modelling (FDM) is a 3D printing technique that can be used to create a 3D pharmaceutical dosage form by employing drug loaded filaments…

Although not readily accessible yet to many community and hospital pharmacists, fuse deposition modelling (FDM) is a 3D printing technique that can be used to create a 3D pharmaceutical dosage form by employing drug loaded filaments…

Multiple carriers may be used to prepare solid dispersions (SDs) for different purposes. The aim of this work is to investigate the effect of the third component on the physical stability and physical aging behavior of cinnarizine-soluplus…

Hot melt extrusion has been an exciting technology in the pharmaceutical field owing to its novel applicability. Twin-screw granulation presents a great potential and offers many advantages relative to conventional granulation processes.…

Poor water solubility of a drug is a tough and difficult task for researchers and pharmaceutical scientists during the formulation and development of dosage forms. Poor drug solubility often leads to inadequate and variable bioavailability.…