BASF Povidone
Kollidon® The original PVP for solid oral dosage forms
BASF's committment to PVP spans a full portfolio of povidones and related products, seven decades and three continents. From large volume povidones to innovative copovidones,…
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Effect of the third component on the aging and crystallization of cinnarizine-soluplus® binary solid…
Multiple carriers may be used to prepare solid dispersions (SDs) for different purposes. The aim of this work is to investigate the effect of the third component on the physical stability and physical aging behavior of cinnarizine-soluplus…
BASF
Focusing On Your Formulation Needs
At BASF, we are using our expertise in polymer chemistry to ensure successful formulation of pharmaceutical medicines, by providing excipients of outstanding quality and performance. From drug…
Synergistic Effect of Polyvinyl Alcohol and Copovidone in Itraconazole Amorphous Solid Dispersions
The first objective is to evaluate the feasibility of melt-extruding polyvinyl alcohol-based amorphous solid dispersions for oral drug delivery. The second objective is to investigate the miscibility between polyvinyl alcohol 4-88 and…
Application of 3D printing technology and quality by design approach for development of…
Pediatric population is a sensitive sector of the healthcare and pharmaceutical field with additional needs compared to the adult population. Extemporaneous formulations for children are generally prepared by manipulating adult…
Solid state characterisation and taste masking efficiency evaluation of polymer based extrudates of…
22. February 2018 Hot melt extrusion has gained considerable attention as a novel technique for taste masking of bitter APIs. The aim of this study was to investigate…
Improvements of theobromine properties using solid dispersions prepared with new technologies
06. November 2017
Abstract
The aim of this study was to improve the pharmaceutical properties of theobromine (TB), particularly its flowability and dissolution rate, by preparing solid dispersions using different…
Stability-Enhanced Ternary Solid Dispersions with HPMC and Soluplus
24. September 2017
Abstract
The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus®polymers for enhanced physicochemical stability and solubility of…
Hot melt extrudates formulated using design space: improved palatability and dissolution
31. August 2017
This work aimed to obtain an optimized itraconazole (ITZ) solid oral formulation in terms of palatability and dissolution rate by combining different polymers using hot melt extrusion (HME), according toa…
PEO Hot Melt Extrudates for Controlled Drug Delivery: Importance of the Molecular Weight
26. September 2016
Abstract
Poly(ethylene oxide) (PEO)-based hot melt extrudates offer an interesting potential as oral controlled drug delivery systems and can provide additional advantages, such as reducing the risk of…