Comprehensive understanding of an integrated continuous pharmaceutical technology was achieved in this study by a combining design of experiments and mechanistic modeling-based simulations. The powder to granule line consisted of twin-screw…

This work is concerned with the semi-mechanistic prediction of residence time metrics using historical data from mono-component twin screw wet granulation processes. From the data, several key parameters such as powder throughput rate,…

Alginates are biopolymers that have been investigated for their use in food and medical fields. Minimal information is available regarding their potential application as tablet superdisintegrants. Here we studied the disintegration action…

Changing relative humidity levels challenge the manufacturing of chewable xylitol-sorbitol based tablets. The aim of the study is to investigate how the formulation of chewable xylitol-sorbitol tablets affects the properties of the powder…

BENEO presents galenIQ™ 721 for highly flowable and stable sachet powders Mannheim (Germany), April 2021 – Sachets are a popular pharmaceutical and nutraceutical packaging format for consumers and manufacturers alike. To ensure accurate…

This study demonstrated the first case of combining a novel continuous granulation technique with powder-bed fusion-based selective laser sintering (SLS) process to enhance the dissolution rate and physical properties of a poorly…

We had a webinar with the experts from BENEO to find out more on galenIQ™. See here some answers to the questions asked from participants of the webinar and have a look at the full webinar recording.  galenIQ™ is a soluble filler and…

Stability studies represent an essential component of pharmaceutical development, enabling critical evaluation of the therapeutic potential of an active pharmaceutical ingredient (API) or a final pharmaceutical product under the influence…

Brussels, 23 March 2021 EXCiPACT asbl is pleased to announce that the Rettenmeier Iberica SL y Cia S.C site in Barcelona, Spain has recently been awarded an EXCiPACT GDP Certificate from Aenor, one of EXCIPACT’s internationally…

The U.S. Food and Drug Administration (FDA) emphasizes drug product development by Quality by Design (QbD). Critical material attributes (CMAs) are a QbD element that has an impact on pharmaceutical operations and product quality.…