Excipients are critical components of a biotherapeutic product as they have a direct impact on the product's stability and hence on its safety and efficacy. A typical biotherapeutic drug product has a variety of excipients and these need to…

The aim of the present investigation was to develop a solid dispersion of itraconazole (ITR) using sacrificial excipients like pregelatinized starch and spray-dried lactose alongside hydroxypropyl methylcellulose and Poloxamer 188, thereby…

In this work, lignin was spray dried with sodium lauryl sulphate (SLS) in order to improve the compaction properties of lignin. Bulk level and physicochemical properties of spray dried formulations were measured and compared to as-received…

Despite being the most essential nutrient, water is commonly forgotten in the fields of pharmacy and nutrition. Hydration status is determined by water balance (the difference between water input and output). Hypohydration or negative water…

The assessment of polymorphism is a problematical issue for regulatory agencies, because variations among crystalline forms of active pharmaceutical ingredient (API) can lead to changes in the efficacy and safety of formulated product. Such…

We are very excited to announce the winners of the 2018 Pharma Excipients Poster Award! With this poster award we wanted to increase the visibility of all the work put into preparation of pharmaceutical and excipient posters for the…

Plants act as a major source of medicines and are used to formulate various pharmaceutical preparations. Apart from this, they act as excellent pharmaceutical aids as well as excipients. Objective: An effort has been made for the…

The major part (approx. 80%) of new drug actives are poorly soluble. Several techniques are used to enhance solubility including but lot limited to alternative salt forms, particle size reduction and solubility-enhancing excipients.…

In this study, we develop and apply a high-throughput screening pro- tocol to investigate the activity of non-ionic surfactants, with a broad range of hydrophilic–lipophilic balance values, against ABCB1-mediated efflux transport and…