09. August 2017 The present study was done for improvement of solubility and thereby bioavailability of Cefixime for its e cient an microbial activity by using amphiphilic…
11. July 2017 Polymers and surfactants impact stability and long-term performance. Access to high-throughput synthesis and screening technologies has enabled…
01. June 2017
Amorphous solid dispersions (ASD) are a common formulation approach for orally delivered small molecule active pharmaceutical ingredients (APIs) whose oral bioavailability (BA) is limited by…
25. May 2017 Abstract The alarming numbers of poorly soluble discovery compounds have centered the efforts towards finding strategies to improve the solubility. One of…
17. May 2017 Changes in the way new chemical entities are developed and identified have led to a situation where many active pharmaceutical ingredient (API) innovations…
19. April 2017
Abstract
We developed a step-by-step experimental protocol using differential scanning calorimetry (DSC), dynamic vapour sorption (DVS), polarized light microscopy (PLM) and a small-scale dissolution apparatus…
29. March 2017 Abstract It was demonstrated in this study that the treatment of physical mixtures of hyaluronic acid (HA) and oncology drugs raloxifene, letrozole, and…
29. March 2017 Abstract Due to the instability of esomeprazole magnesium dihydrate (EPM), a proton pump inhibitor, in gastric fluid, enteric-coated dosage form is…
26. March 2017 Aim: The therapeutic efficiency of a formulation will depend on various crucial parameters such as solubility of the drug, stability of the compound,…
21. February 2017 Abstract: The aim of this work was to develop cefdinir solid dispersions (CSDs) prepared using hydrophilic polymers with enhanced dissolution/solubility…