This review presents the possibilities of oral delivery of insulin. Insulin, being readily destroyed/transformed by the proteolytic enzymes and first-pass effects in the digestive system, has mainly been administered through injection,…

To face the challenges of oral delivery of peptide and protein drugs (P/P drugs), self-emulsifying drug delivery systems (SEDDSs) containing monoacyl phosphatidylcholine (MAPC), Labrasol (LAB) and medium-chain (MC) monoglycerides as…

In this article, a new type of mesoporous carbon nanoparticles (MCN) was fabricated as a potential oral delivery system of insulin to reduce the adverse reactions by hypodermic injection. The mesoporous carbon nanoparticles-carried insulin…

13. September 2018 The study aimed at investigating the potential of spray drying method for encapsulation of protein drugs into solid lipid microparticles (MP) and evaluating effects of excipients on encapsulation and release of protein…

07. January 2018 Abstract The objective of this study was to design intestinal mucus-penetrating core-shell nanocomplex by functionally mimicking the surface of virus,…

11. September 2017 Abstract Nanoparticles have demonstrated significant advancements in potential oral delivery of insulin. In this publication, we review the current…