Learn more about the use of sugar spheres in this video from pharm-a-spheres™. Sugar spheres (also called neutral pellets, nonpareil seeds, microgranules or sugar beads) are produced, preferably using a layered sugar-coating structure.…

7 October 2020 & 13 October 2020 – both 12:00 PM EST, 9:00 AM PST Using Speciality Excipients from Fuji Chemical Industries to Develop High Quality Medicine. Join Fuji in their upcoming Webinar on how to solve your…

Diclofenac sodium was used as a model drug for preparation of delayed-release (DR) multiparticulates, which were further processed into solid oral dosage forms such as capsules and tablets. Multiple unit pellets systems (MUPS) were prepared…

In drug development here is no one-size-fits-all approach which can be applied to allactive pharmaceutical ingredients (APIs). The best formulations and solutions depend on many characteristics, including the API characteristics, route of…

The compaction of multiple unit-pellet system (MUPS) tablets poses considerable challenges due to potential compaction-induced damage to the functional polymer coat and segregation of pellets from other excipients during the tableting…

The multiple-unit sustained-release (MUSR) dosage forms containing numerous sustained-release subunits present a reliable choice for oral formulation of controlled release systems. As a typical MUSR, the metoprolol succinate…

Advantages of Hot Melt Coating (HMC) One advantage for the pharmaceutical industry is the simplification of complex dosage schemes, as several active ingredients can be combined, even those that cannot normally be combined. As the…

A design of experiments (DOE) approach (2-level full factorial design) was used to investigate the effect of several formulation and process variables on the properties of fast disintegrating tablets comprising starch-based pellets and…

The goal of the present study is to prepare a stable, multiple-unit, extended-release dosage form containing oxycodone pellets coated with aqueous ethylcellulose (EC) dispersion, Surelease E-7-19050. The application of 18% w/w of EC leads…