30. September 2016
ABSTRACT
Oral dosage form is the physical form of a dose of a chemical compound used as a drug or medication intended for administration or consumption by the oral route. The poor dissolution rate of…
17. June 2016
Recent Advances in Drug Delivery and Solubility Enhancement Based on Cellulosic Polymers - Second Scientific Seminar in North America
Recent Advances in Drug Delivery and Solubility Enhancement Based…
18. April 2016 Deep eutectic solvent (DES) is a room temperature liquid typically formed by mixing two solid compounds, such as a quaternary ammonium salt (QAS) (e.g.…
10. June 2015 Dissolution and Solubility Enhancement of the Highly Lipophilic Drug Phenytoin via Interaction with Poly(N-isopropylacrylamide-co-vinylpyrrolidone) Excipients -…
Nimodipine, a member of calcium channel blocker, specifically binds to L-type voltage-gated calcium channels. The maximum solubility of nimodipine was found at pH 1.2 and solubility decreases up to pH 4.0. At a pH 6.0 and higher pH,…
Abstract
Crystalline carriers such as dextrose, sucrose, galactose, mannitol, sorbitol, and isomalt have been reported to increase the solubility, and dissolution rates of poorly soluble drugs when employed as carriers in solid dispersions…