SYNOPSIS Controlled release (CR) formulations are revolutionizing drug delivery across the pharmaceutical landscape. Offering advantages like enhanced therapeutic outcomes and patient convenience, this innovative drug formulation is…

The microencapsulation of α-tocopherol based on the complex coacervation of low-molecular-weight chitosan (LMWC) and sodium lauryl ether sulphate (SLES) without harmful crosslinkers can provide biocompatible carriers that protect it from…

Since the introduction of HPMCP (hypromellose phthalate USP/NF, JP, EP) in 1971, it has proved its value in enteric coating using organic solvent. The chemical structure of HPMCP is a monophthalic acid ester of hypromellose.The threshold pH…

Abstract The aim of the present study was to investigate the gastroretentive capacity of different formulation principles. This was indirectly determined by the absorption behavior of caffeine from the dosage forms. A slow and continuous…

People worldwide need to improve their health or intention to control diseases more naturally through ingredients incorporated into foods and beverages, called functional foods. Functional foods include probiotic organisms and bioactive…

Abstract In the nasal cavity, nasal mucosa had a high blood perfusion rate, due to this the absorption of the drug is high as compared to other routes, as well as has increased good bioavailability of drugs at the systemic circulation. To…

Hydroxy propyl methyl cellulose (Hypromellose) and methyl cellulose are produced by Shin-Etsu Chemical Co., Ltd. since 1960s under the trade name METOLOSE®. For methyl cellulose, several grades are available, and they differ in…

Would Nanocarriers Complement Biofilm Disruption or Pave Its Road? Introduction: Cystic fibrosis (CF) is associated with pulmonary Pseudomonas aeruginosa infections persistent to antibiotics. Methods: To eradicate pseudomonal biofilms,…

Abstract TPGS (D-α-tocopheryl polyethylene glycol 1000 succinate) polymeric micelles show interesting properties for ocular administration thanks to their solubilization capability, nanometric size and tissue penetration ability.…

The goal of this study was to formulate tacrolimus nanogel based on nanostructured lipid carrier (NLC) in order to improve the efficacy, aesthetic, and patient compliance for the treatment of psoriasis. The microemulsion method was used to…