In its 33 years, ADDR has published regularly on the potential of oral delivery of biologics especially peptides and proteins. In the intervening period, analysis of the preclinical and clinical trial failures of many purported platform…

This review presents the early history, the motivation, the research and some of the backstories behind the discovery and development of sulfobutylether-β-cyclodextrin as a novel parenterally safe solubilizer and stabilizer. A specific…

Food and Drug Administration (FDA) has approved a drug product (Spritam®) and many medical devices manufactured by 3-dimensional printing (3DP) processes for human use. There is immense potential to print personalized medicines using 3DP.…

Fulvic acid, a humic substance often considered as a geopolymer, extracted from different natural resources like Shilajit, Peat, dissolved organic matters, etc. There are several reports of its pharmacological properties and its potential…

Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal molecules described to date are cytotoxic. We…

Excipients Included in U.S. Vaccines, by Vaccine In addition to weakened or killed disease antigens (viruses or bacteria), vaccines contain very small amounts of other ingredients – excipients. Some excipients are added to a…

The overall nutraceuticals market is growing at a higher rate than pharmaceuticals. However, the growth in the nutraceutical market does not entirely translate to excipients market growth for nutraceutical OSDFs. The reason: Excipients are…

D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) is a pharmaceutical excipient approved by Chinese NMPA and FDA of USA. It’s widely applied as a multifunctional drug carrier for nanomedicine. The advantages of TPGS include…

Working with the Netherlands Organization for Applied Scientific Research (TNO), DFE Pharma tested 20 lactose grades in 3D powder bed printing. The primary objective of this study was to select lactose with sufficient flow, wetting and…

Fuliginous Management Ltd is a service providing company to the Contract Manufacturing Market, supporting both CMOs and Pharma Companies cooperating with CMOs. Get prepared for 2021 and acquire the updated CDMOs capibility mapping.…