BASF Povidone
Kollidon® The original PVP for solid oral dosage forms
BASF's committment to PVP spans a full portfolio of povidones and related products, seven decades and three continents. From large volume povidones to innovative copovidones,…
Categories:
A microcrystalline cellulose based drug-composite formulation strategy for developing low dose drug…
The uniformity of active pharmaceutical ingredient (API) is a main challenge associated with manufacturing low dose tablets. Here, we present a binder enhanced API-microcrystalline cellulose (BEAM) approach to address this challenge. In the…
Temperature: an overlooked factor in tablet disintegration
Disintegration is the first event in the bioavailability cascade after the ingestion of immediate release tablets. Although the influence of various physico-chemical parameters of media on tablet disintegration has been investigated in…
Film Coating excipients and systems by manufacturer
The procedure of coating tablets is a complex process that results in the forming of a thin layer around the tablet.
Film coating is applied to a wide variety of pharmaceutical products, including tablets, pellets, granules, capsules,…
DC Excipients – A list of excipients for direct compression
Direct compression (DC) the fastest and most economic way to manufacture a tablet as it directly goes from powder mixing to tableting without any further production steps. It plays a key role in continuous manufacturing thanks to the high…
Fully inkjet‐printed glucose assay fabricated on highly porous pigment coating
A simple paper-based microfluidic device, fabricated on a highly porous coating consisting of functionalised calcium carbonate (FCC) pigment and a microfibrillated cellulose (MFC) and/or polyvinyl alcohol (PVOH) binder, was developed for…
Compaction behavior of isomalt after roll compaction
Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow taste masking, the low glycemic and insulinemic response (Petzoldt, 1982), and the ability to be compacted directly. With…
Solidification of SMEDDS by fluid bed granulation and manufacturing of fast drug release tablets
Solidification of self-microemulsifying drug delivery systems (SMEDDS) is a rising experimental field with important potential for pharmaceutical industry, however fluid-bed granulation with SMEDDS is yet an unexplored solidification…
Delta-mannitol to enable continuous twin-screw granulation of a highly dosed, poorly compactable…
In current study, it was investigated if the moisture-mediated polymorphic transition from δ- to β-mannitol during twin screw granulation (TSG) also took place in high drug loaded formulations and if the specific granule morphology…
Development of alginate esters as novel multifunctional excipients for direct compression
Methyl ester derivatives of alginic acid have been evaluated as potential multifunctional excipients for pharmaceutical direct compression. The use of alginic acid as an excipient in tablet formulation is limited because of certain…