Repurposing drugs such as the FDA-approved niclosamide is a highly efficient way to leverage drugs with known safety profiles to fight the coronavirus outbreak. College of Pharmacy researchers at The University of Texas at Austin are now…

Intraoral lidocaine formulations are applied in children and adults for pain relief. The potential risks associated with orally administered lidocaine due to accidental ingestions were highlighted in a warning letter by the US Food and Drug…

Repurposing drugs such as the FDA-approved niclosamide is a highly efficient way to leverage drugs with known safety profiles to fight the coronavirus outbreak. College of Pharmacy researchers at The University of Texas at Austin are now…

Summary: Inactive ingredients and generally recognized as safe compounds are regarded by the US Food and Drug Administration (FDA) as benign for human consumption within specified dose ranges, but a growing body of research has revealed…

Non-small cell lung cancer (NSCLC) is a global disorder, treatment options for which remain limited with resistance development by cancer cells and off-target events being major roadblocks for current therapies. The discovery of new drug…

Aim It was the aim of this study to synthesize a phosphorylated emulsifier possessing a PEG-linker for establishment of a potent zeta potential changing system in self-emulsifying drug delivery systems (SEDDS). Methods…

Do you want to use the USP Pending Monograph process? Or have you ever wondered what the USP Pending Monograph process is and how it works in detail? See our article explaining the PMP with a full overview or have a look at our summarizing…

Despite the legislative initiatives by the regulatory European medical agency (EMA) and the United States Food and Drug Administration Authority (FDA), an approved drug with child-appropriate dosage formulations are still absent for many…

Novel excipients play a crucial role in bringing new, improved and safer drugs to the pharmaceutical market. There are however significant challenges in the development of innovative excipients, mainly because of the absence of globally…