A compatibility study of drug substance with excipients is a crucial step in the drug development process in order to generate potent final drug formulations for efficient and safe therapy for various diseases. Thus, the development of new…

The pressure to innovate faster than their competitors has drug formulators exploring new ways to optimise manufacturing processes Article in manufacturingchemist.com Continuous manufacturing, for example, has evolved at a relatively fast…

We congratulate Merck for winning the Award with Parteck® MXP excipient for hot melt extrusion. Here some information on the product: Enhanced API Solubility and Stable, High Drug LoadsPoor solubility of APIs is a critical challenge in drug…

The small intestine mucosal barrier is physiologically regulated by the luminal conditions, where intestinal factors, such as diet and luminal tonicity, can affect mucosal permeability. The intestinal barrier may also be affected by…

The formulation of amorphous solid dispersions (ASDs) is an effective way to improve the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). The combination of an amorphous state of the drug and the presence of…

13. September 2018 The study aimed at investigating the potential of spray drying method for encapsulation of protein drugs into solid lipid microparticles (MP) and evaluating effects of excipients on encapsulation and release of protein…

A very informative overview by Gattefossé on its excipients and uses thereof. Lipid excipients for suppository and pessary formulation include hard fat and hard fat with additives. These bases provide excellent physico-chemical stability…