Topical ocular delivery of therapeutics are always a challenging arena in order to achieve high ocular bioavailability with safe administration. Ideal ocular delivery of drug required 4 P's that is Patient compliance, Prolong retention,…

Topical psoralens plus ultraviolet A radiation (PUVA) therapy consists in the topical application of 8-methoxypsoralen (8-MOP) followed by the skin irradiation with ultraviolet A radiation. The employment of classical 8-MOP vehicles in…

pharma's almanac - September 29, 2020 PAP-Q3-20-CL-024 - Shiksha Mantri, Ph.D. - Adela Kasselkus, Ph.D. Lipid-based drug delivery systems offer several advantages, including improving the stability, solubility, bioavailability, and…

Background Nanocellulose, which possesses great physical, chemical, and biological properties, is a natural polymer derived from widely available native cellulose. It has outstanding properties such as high mechanical strength, stiffness,…

An increasing number of protein vaccines have been researched for cancer, inflammation, and allergy therapies. Most of the protein therapeutics are administered through injection because orally-administered proteins are metabolized by the…

More than 10 years after the Paediatric Regulation came into place there is still a strong need for pure paediatric medicines for off-patent drug substances. Numerous compounds for which a paediatric formulation does not exist can be found…

ZoomLab™ is the Virtual Pharma Assistant from BASF.  Pharma Excipients had the chance to interview one of the "masterminds" behind ZoomLab™, Dr. Ferdinand Brandl. Ferdinand answered all our questions on ZoomLab™. See the video of the…

Gastrointestinal adverse effects such as esophageal irritation and ulcers are the major disadvantages of the oral administration of alendronate (ALD) and nitrogen-containing bisphosphonate. We hypothesized that the transdermal delivery of…