The development of new orally inhaled drug products requires the demonstration of safety which must be proven in animal experiments. New in vitro methods may replace, or at least reduce, these animal experiments provided they are able to…

Article By Dr. Catherine Sheehan - Senior Director of Science – Excipients at the United States Pharmacopeial Convention With significant innovations in pharmaceuticals, including biologic drugs and treatments for rare diseases, the need…

The novel polymeric particulate systems show high potential in their clinical effectiveness. Nevertheless, many of the drug delivery systems developed in the research laboratories have not found their way to clinics. The lack of…

Disulfiram (DSF) is an FDA-approved drug that has been repurposed for cancer treatment. It showed excellent anticancer efficacy in combination with copper ions (Cu). Several active clinical trials testing the anticancer efficacy of DSF…

RCA Bignami Srl was founded in 1994 and after many years of intense activities, experience and continuous innovation, today is a leading corporation in the industry. The company plays an important role not only in the rotary dies and…

Innovation drives progress in the development of new drugs and therapeutic biological products. 48 new drugs and biological products were approved by the FDA last year, which means new treatment options for patients and…

Disulfiram (DSF), an FDA-approved anti-alcoholic drug, has recently shown that it possesses anti-cancer effects. However, DSF is hydrophobic in nature with less stability. Therefore, new approaches are required for the effective delivery of…

Article by Omar Sacirbay - mjbizmagazine As an emergency room physician and the founding CEO of Vireo Health, a multistate marijuana company based in Minnesota, Kyle Kingsley had thought extensively about how cannabinoids could replace…

Innovation drives progress. When it comes to innovation in the development of new drugs and therapeutic biological products, FDA’s Center for Drug Evaluation and Research (CDER) supports the pharmaceutical industry at every step of the…

Aims Apelin and vitamin E have been proposed as signaling molecules, but their synergistic role is unknown. The aim of this work was to develop vitamin E TPGS/Apelin system to test their cardioprotective and metabolic efficacy in…