The new book "Tubercular Drug Delivery Systems - Advances in Treatment of Infectious Diseases" book targets new advances in areas of treatment and drug delivery sciences for tuberculosis.  It covers advances in drug therapy and drug…

Compaction simulators are a key technology allowing scientists to develop formulations and troubleshoot tablet defects. It means that formulation scientists or tech transfer engineers can assess the influence of process parameters on…

PRESS RELEASE Essen, Germany, March 8, 2023 New GMP facility for clinical and small-scale commercial pharmaceutical lipids Supports all types of custom and proprietary lipids Reinforces Evonik’s position as integrated…

Don’t let poor solubility affect your innovative drug projects Approximately 60% of potential active pharmaceutical ingredients (APIs) under development, and more than 40% of those in reformulation, are poorly water soluble1.…

Abstract Introduction Mucoadhesive drug delivery systems (MDDS) are specifically designed to interact and bind to the mucosal layer of the epithelium for localized, prolonged, and/or targeted drug delivery. Over the past 4…

Although previous research demonstrated improved flowability, packing, fluidization, etc. of individual powders via nanoparticle dry coating, none considered its impact on very low drug loaded blends. Here, fine ibuprofen at 1, 3, and 5 wt%…

Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants are drugs that can inhibit the body’s immune response. Considering drug side effects such as hepatorenal toxicity and the unique structure of the eye,…

Powder mixing unit operations are essential to the manufacturing of pharmaceutical drug substance and drug products. To model powder mixing, computational approaches have been used to evaluate mixing indices for different types of mixers,…

The aim of this study was to develop, characterize and evaluate the in vivo oral efficacy of self-emulsifying drug delivery systems (SEDDS) containing fexinidazole (FEX) in the experimental treatment of visceral leishmaniasis (VL). The…

The history and evolution of Nucleic Acid Delivery systems mRNA and liposomes were both first discovered in the 1960s, and liposomes were used to deliver mRNA into eukaryotic cells in 1978.1,2 Even with the ability to inject mRNA into…