The widespread use of materials produced from petrochemical substrates, such as plastics, can exert an adverse impact on the environment, especially on creatures living therein, including fish and turtles in the sea, as well as the birds…

The three dimensional printing (3DP) in the pharmaceutical domain constitutes an alternative, innovative approach compared to the conventional production methods. Fused deposition modelling (FDM), is a simple, cost-effective 3DP technique,…

Background: Oral bioavailability of gliclazide, a hypoglycemic drug, is hindered by its low aqueous solubility. Improvement of solubility will enhance dissolution rate and in turn the bioavailability. This research aimed to formulate the…

Cyclosporine (CsA) has a selective property of suppressing various T-lymphocyte functions. This is of utmost importance in preventing allograft rejection by several organ transplantations, as well as in the treatment of systemic and local…

Two pharmaceutical polymers with high glass transition temperatures (Tg>100°C), polyvinylpyrrolidone-vinyl acetate copolymer (PVPVA) and hydroxypropyl methylcellulose acetate succinate (HPMCAS), have been assessed for their impact on the…

Epilepsy is the most common chronic brain disorder and affects millions of people worldwide. Carbamazepine (CBZ) is one of the first-line pharmacological therapy instituted to patients due to its wide spectrum of action. Although marketed…

The use of natural polymer as excipients in pharmaceutical sector is expanding day by day. Low cost, safety degradable are the main causes that make them differ from other sources. Natural sources have wide range…

The aim of this research was to use inkjet printing technology in formulation of personalized medicine. Thus in this research, an attempt was made to print OTF by TIJ printing. A placebo solution comprising of different polymers and polymer…

Solid dispersions production is one of the substantial approaches for improvement of poor drug solubility. Additionally, supercritical fluid assisted method for preparation of solid dispersions can offer many advantages in comparison to the…

Anti-HIV drug Lamivudine exhibit shorter half-life (2 h) and poor bioavailability (62% in paediatric patients), multiple dosing is required. To overcome the limitations, nanoparticles loaded buccal film was developed for prolonged drug…