The influence of different isomalt particle morphologies on dry granule and tablet properties was investigated. Primary crystals, milled particles and agglomerates were tableted after roll compaction/dry granulation and compared to the…

Kollidon® 30 is the solution for endless opportunities in pharmaceutical formulations – use it as a binder, pore former, stabilizer, thickener, solubilizing agent, crystallization inhibitor and countless more. Click on the poster to see it…

Copovidone and crospovidone are commonly used excipients in solid oral dosage forms for many decades. Typically, copovidone is used as dry binder and crospovidone as disintegrant in tableting formulations. The use of dry binder and…

The aim of this study was to solidify a ticagrelor loaded self-microemulsifying drug delivery system (TCG-SM) with enhanced dissolution and bioavailability of ticagrelor (TCG) for developing TCG-SM granules and tablets. TCG was dissolved…

The application of process analytical technologies (PAT) to monitor critical quality attributes (CQAs) provides an important approach to enhance process understanding and improve the reliability of pharmaceutical production processes.…

The application of process analytical technologies (PAT) to monitor critical quality attributes (CQAs) provides an important approach to enhance process understanding and improve the reliability of pharmaceutical production processes.…

BIOGRUND’s one-step tabletting agent CompactCel® SIL provides an easy to use, granulated and homogeneous compound of Silica and PVP/NaCMC or HPC/NaCMC, which acts as a perfect dry binder granulate. With CompactCel® SIL it is possible to…

The study focused on the fluid-bed granulation process of a product with two active pharmaceutical ingredients, intended for coated tablets preparation and further transfer to industrial scale. The work aimed to prove that an accurate…