JRS Pharma
JRS Pharma is a leading manufacturer of excipients, offering a complete portfolio of excipient solutions for the pharmaceutical and nutraceutical industries. Our excipients portfolio includes: high functionality excipients, binders,…
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Application of lactose in the pharmaceutical industry
This chapter describes the application of lactose as excipient in the pharmaceutical industry. About 60%–70% of pharmaceutical dosage forms contain lactose, and in volume it is one of the biggest pharmaceutical excipients.
Lactose can…
Modelling of pharmaceutical formulations for continuous twin-screw wet granulation: Determination of…
Two-dimensional population balance model (PBM) is developed in order to model pharmaceutical granules formation in a twin-screw wet granulator. Granule size and liquid content are considered as internal coordinates, while axial length of…
Material Attributes and Their Impact on Wet Granulation Process Performance
1 Granulation Technology
Granulation technology is commonly used in the pharmaceutical industry during solid oral dosage form development, especially in tablet and capsule manufacturing (Parikh, 2010; Shanmugam, 2015). The process commonly…
Three-Dimensional Printing of Cell Exclusion Spacers (CES) for Use in Motility Assays
Migration and invasion (migration/invasion) assays are common methods used to study cell motility, development, inflammation, wound healing and invasion of malignant cells in cancer.
In migration/invasion assays, several approaches…
An Overview of 3D Printing Technologies for Soft Materials and Potential Opportunities for…
Purpose
Three-dimensional printing (3DP) is a rapidly growing additive manufacturing process and it is predicted that the technology will transform the production of goods across numerous fields. In the pharmaceutical sector, 3DP has…
Formulation and optimization of lyophilized nanosuspension tablets to improve the physicochemical…
Silymarin (SLM) is a hepatoprotective herbal drug characterized by low aqueous solubility and, consequently, low oral bioavailability. The objective of this study was to enhance the physiochemical properties of SLM, through preparation and…
Clay nanotubes as a novel multifunctional excipient for the development of directly compressible…
Halloysite is a unique biocompatible aluminosilicate clay mineral with powder particles predominantly comprising of concentrically rolled nanotubular aggregates. Some recent studies have also contributed to its prospective case in oral drug…
Enhancing dissolution of artesunate from immediate release tablets using a green granulation…
Artesunate is a poorly soluble drug and liable to aqueous hydrolysis. This study aims to formulate Artesunate as an immediate release tablet through optimization of the melt granulation technique to improve the dissolution of the drug.…
Review on plant derived excipients
Plants act as a major source of medicines and are used to formulate various pharmaceutical preparations. Apart from this, they act as excellent pharmaceutical aids as well as excipients.
Objective:
An effort has been made for the…