A professional guide to 3D and 4D printing technology in the biomedical and pharmaceutical fields 3D and 4D Printing in Biomedical Applications offers an authoritative guide to 3D and 4D printing technology in the biomedical and…

Modified- or sustained-release matrices are designed to release a drug slowly over an extended period of time. Formulations must be robust to ensure drug release over time and avoid dose-dumping. Lipid-based matrices are water-insoluble and…

It is widely recognized that many Active Pharmaceutical Ingredients (APIs) are bitter, some extremely so. But bitterness is not the only challenge in creating palatable, patient-accepted drug products. If not bitter, what are other common…

Oral administration is the most accepted and favored route as various side effects such as fear, pain and risk of infections can be avoided resulting in a comparatively high patient compliance. However, from the industrial point of view the…

Broadly speaking, there are three categories of sweeteners – nutritive, sugar alcohols, and high intensity. Sweetener selection is informed by technical, regulatory and clinical considerations as described in the Introduction to Sweeteners.…

Most of the recent drug compounds coming out of the drug discovery pipeline are labile (multiple polymorphs), and need to be developed into robust marketed oral drug formulations. There are only 22 oral macroamorphous drug products approved…

A swallowing disorder, known as dysphagia, is a phenomenon of increasing prevalence. It may occur because of various medical conditions involving the oral cavity, the pharynx, the esophagus, and the gastro-esophageal junction. The US FDA…

Did you know that Kollidon® 12 PF and Kollidon® 17 PF are highly suitable for injectable formulations? Kollidon® 12 PF/ Kollidon® 17 PF low molecular weight make them particularly suitable for parenteral applications. Additionally, they are…

Increasing patient adherence to medication regimens remains a top priority in the pharmaceutical industry. Simultaneously, consumers/patients are looking for dosage forms that are easy to take and that will not disrupt their everyday “on…