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Significance of excipients to enhance the bioavailability of poorly water-soluble drugs in oral…

Dec 11, 2017

11. December 2017 Nowadays most of the drug substances are coming into the innovation pipeline with poor water solubility. Here, the influence of excipients will play a…

Alfuzosin Hydrochloride ODTs with Risk Evaluation via Quality by Design

Nov 25, 2017

25. November 2017 In this study, within the framework of Quality by Design which is a systematically scientific approach which enables to understand and control the…

Nanotechnology

improvement of fine powders through nano-coating

Oct 25, 2017

25. October 2017 Majority of the pharmaceutical dosage forms are manufactured from powders as a starting material. The handling and processing problems in pharmaceutical manufacturing still revolves around unpredictable…

News

Fast disintegrating tablet of Valsartan for the treatment of pediatric hypertension

Oct 21, 2017

21. October 2017 Fast disintegrating tablets (FDTs) dissolve or disintegrate in the mouth without the need of additional water. The aim of the present study was to formulate…

Comparative disintegrant action study using Kohonen’s self-organizing maps

Oct 17, 2017

17. October 2017 To gain a better understanding of disintegration actions, 11 different disintegrants were tested. Model tablets were prepared with various preparation…

News

Excipients labelling – EMA information

Oct 13, 2017

13. October 2017 The European Medicines Agency (EMA) publishes information on excipients for inclusion in the labelling and package leaflet of human medicines. EMA excipient definition: "An excipient is a…

Oral Time-Controlled Release Etodolac Pellets

Sep 21, 2017

21. September 2017 Abstract The objective of this study was to prepare time-controlled release etodolac pellets to facilitate drug administration according to the body’s…

Evaluation of tablet punch configuration on mitigating capping by a quality by design approach

Sep 2, 2017

02. September 2017 Abstract Capping is a common problem in the manufacture of some types of tablets and unless resolved, the tableting process cannot proceed. Hence, all…

News

Wheat in pharmaceutical Excipients – which excipients are based on it – is it a gluten…

Aug 18, 2017

18. August 2017 How many wheat (derived) excipients contain wheat / wheat starch as apotential source of Gluten? Based on available information most of the excipients such as Sodium StarchGlycolate, Pregelatinized…

An investigation into the effects of excipient particle size, blending techniques and processing…

Aug 15, 2017

15. August 2017 Abstract Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contrib- uting…

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