Background: To develop a first-time-novel polymeric NPs from PLGA and their coating by Chitosan (CS) of Melatonin (MT) for the enhancement of lungs bioavailability by targeting lungs from the nose. Materials and Methods: The Melatonin…

Based on the biocompatibility and macrophage targeting of natural polysaccharides, combined with the physiological and pathological characteristics of the gastrointestinal tract and colonic mucosa of ulcerative colitis (UC), we prepare…

Advances in existing drying techniques are essential for upgrading large scale industries. Enzymes are often degraded by drying processes. Spray drying (SD) has detrimental effects on bioactive molecules at high temperatures. Freeze-drying…

The polymer coated polymeric (PCP) microneedles (MNs) is a novel approach for controlled delivery of drugs (without allowing release of the excipients) to the target site. PCP MNs was explored as an approach to deliver the drug…

The development of intensification technology for spouted beds has become a current research focus, and an effective way to improve the efficiency of spouted beds is to reform their structure. Although numerous studies have been conducted…

Growing evidence suggests quercetin and aspirin may have anticancer properties, notably in the case of colorectal cancer. The goal of this study was to create Pluronic F127 and polyethylene glycol 4000 solid dispersion-loaded chitosan…

Ziprasidone hydrochloride Monohydrate ZHM, chemically 5- ethyl]-6-chloro-1, 3-dihydroindol-2-one hydrochloride; is an atypical antipsychotic with very poor water solubility and less oral bioavailability. The presented research work is about…

This research aims to develop a drug delivery system that effectively treats colitis while administering curcumin/mesalamine by coating alginate/chitosan beads with Eudragit® S-100 to target the colon. Beads were tested to determine their…