galenIQ™ is a sweet-tasting water soluble filler binder derived from sugar beet. It is available in several different morphological forms which are suitable for the formulation and manufacture of oral solid dosage forms including tablets,…

Scale up of manufacturing processes is an important step in drug development – not to say: a big hurdle! The Wurster (bottomspray) fluidized bed process is based on a clear technical concept. For scale up, configuration of the process…

Scale up of manufacturing processes is an important step in drug development – not to say: a big hurdle! The Wurster (bottomspray) fluidized bed process is based on a clear technical concept. For scale up, configuration of the process…

Background: Multiple dosing is required for bosentan in order to achieve steady-state concentration. Hence formulating bosentan controlled release formulation could be an approach to solve this issue. Objective: The objective is to…

In this webinar Norbert Pöllinger and Tom West presented the unique opportunities offered by the combination of 3D printing and multiparticulates to achieve novel solutions in ODT application. They demonstrated how swallowing issues of high…

Desmopressin acetate (DDAVP) is an oligopeptide indicated for the treatment of primary nocturnal enuresis, for example. The poor oral bioavailability of DDAVP accelerated a shift to alternative routes of administration like nasal and…

Dissertation by Ilias El Aita: Part 1 For years, patients were viewed as a homogeneous group and selected drug treatment was based on experience from clinical studies. Consequently, individual factors such as age, physiological condition…

The formulation of orodispersible minitablets (ODMTs) usually targets the disintegration time and mechanical strength, but should also consider a series of technological issues related to powder flow and compression behaviour. In this…

As the demand for pediatric dosage forms continues to increase across the industry, there can be formulation challenges for this patient population. Pediatric patients may require different dosage forms depending on age ranges, and patient…

The potential of alternative routes of application compared to the traditional oral route is constantly growing. Especially in transmucosal applications for the oral cavity, easy accessibility is an attractive feature with many new…