27. July 2016 Abstract The aim of the presented research was the preparation and in vitro and in vivo evaluation of mucoadhesive oral films containing nystatin.…
18. April 2016 Experimental Studies of the Ability of Pharmacopoeial Excipients to ReleasePharmacologically Active Substances when Developing Dental Dressing The…
24. February 2016
Compression coating technique has been used in formulation of chronotherapeutic drug delivery systems with pulsatile carvedilol release with polyethylene oxide as controlling release agent. FMEA, risk…
18. February 2016
Polyethylene oxide (PEO) has been extensively used as an extended-release excipient in matrix tablets due to its extraordinarily safe, stable, soluble, swellable and erodible properties. The present…
20. January 2016 The flow properties of drug-polymer mixtures have a significant influence on their processability when using techniques such as hot melt extrusion (HME).…
Prescription drug abuse has become a worldwide public health issue. Of particular concern is the dose-dumping effect caused by co-ingestion of ethanol which leads to premature rapid release of the drug load. Also, medications can…
Abstract
This work aimed to develop amphiphilic nanocarriers such as polymersome based diblock copolymer of Kollicoat ® IR −block-poly(ε-caprolactone) (Kollicoat ® IR-b-PCL) for potential co-delivery of Nisin (Ni) and Curcumin (CUR) for…
Transdermal administration remains an active research and development area as an alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral (gastrointestinal side effects, low drug bioavailability, and…
Abstract
Forty-eight (48) drug products (DPs) containing amorphous solid dispersions (ASDs) have been approved by the U.S. Food and Drug Administration in the 12-year period between 2012 and 2023. These DPs comprise 36 unique amorphous…
Apocynin (APO) is a plant derived antioxidant exerting specific NADPH oxidase inhibitory action substantiating its neuroprotective effects in various CNS disorders, including epilepsy. Due to rapid elimination and poor bioavailability,…