Purpose: To determine excipient and ibuprofen: excipient mixture sensitivity to reprocessing produced by either direct compression or wet granulation.
Methods: The effect of excipient type, technology and reprocessing on flow,…
03. August 2015 This study investigates the effects of a variety of coating materials on the flowability and dissolution of dry-coated cohesive ibuprofen powders, with the…
21. June 2015 Abstract Effective assessment and management of wound pain can facilitate both improvements in healing rates and overall quality of life. From a…
07. April 2015 The effect of electrostatic interaction between ibuprofen sodium (IbS) and cationic diethylaminoethyl dextran (Ddex), on the tableting properties and…
P. Müsse, Hochschule Fresenius University of Applied Sciences, 65510 Idstein, Germany / Dr. M. Yunis, BIOGRUND GmbH, 65510 Huenstetten, Germany
Introduction: Dry granulation (roller compaction) as a continuous process…
The possibility of attaining direct compression (DC) tableting using silica coated fine particle sized excipients was examined for high drug loaded (DL) binary blends of APIs. Three APIs, very-cohesive micronized acetaminophen (mAPAP, 7 …
ABSTRACT
This comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation. Dry granulation techniques, including slugging,…