The purpose of this study was to improve tabletability (tensile strength versus compaction pressure) of α-lactose monohydrate by twin screw extrusion (TSE) near its dehydration temperature but below its melting point. When extruded at 150…

In recent years, significant progress has been made in the field of continuous twin screw granulation. However, only limited knowledge is currently available on the impact of active pharmaceutical ingredient (API) properties on granule…

MEGGLE Excipients & Technology. MEGGLE has added GranuLac® 80 to its broad range of milled grade lactose monohydrate excipients. GranuLac® 80 GranuLac® types consist of fine, sharp-edged lactose particles, having cohesive powder…

Shear cell tests have been conducted on twenty different lactose powders, most of which commercially available for oral or inhalation purposes, spanning a wide range of particle sizes, particle morphologies, production processes. The aims…

The whitepaper shows results of tested 20 lactose grades in 3D powder bed printing. The primary objective of this study was to select lactose with sufficient flow, wetting and binding to be used effectively in the powder bed 3D printing of…

Working with the Netherlands Organization for Applied Scientific Research (TNO), DFE Pharma tested 20 lactose grades in 3D powder bed printing. The primary objective of this study was to select lactose with sufficient flow, wetting and…

Building on a long and well established history of supplying world class pharmaceutical grade lactose, film coatings, and tableting systems, Kerry introduces Aero Flo® Inhalation lactose, designed to meet the growing demand for lactose that…

The flowability of powders used in tableting significantly affects tablet weight and content uniformity of active pharmaceutical ingredients. Use of granulated materials instead of powdered materials can improve flowability. In this study,…

This chapter describes the application of lactose as excipient in the pharmaceutical industry. About 60%–70% of pharmaceutical dosage forms contain lactose, and in volume it is one of the biggest pharmaceutical excipients. Lactose can…