QbD in paediatric formulations
10. May 2017 Obtaining formulations for paediatric diseases is one of the major challenges to face in the coming years. EMA, in the Guideline on pharmaceutical development…
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9th Conference of the European Paediatric Formulation Initiative
22. March 2017 19 TO 21 SEPTEMBER 2017 IN WARSAW, POLAND The 9th EuPFI conference series is the ideal forum to learn, grow and to be inspired on the…
Formulating a poorly water soluble drug into an oral solution suitable for paediatric patients;…
28. January 2017 Introduction Many drugs are unavailable in suitable oral paediatric dosage forms, and pharmacists often have to compound drugs to provide paediatric…
DEVELOPMENT OF PAEDIATRIC DOSAGE FORMS OF FUROSEMIDE USING THE PROBLEM STRUCTURING METHOD OF…
24. January 2017 ABSTRACT The lack of age-appropriate (paediatric) authorised medicines is a long-standing problem amongst regulatory authorities, patients, parents and…
Evidence of acceptability of oral paediatric medicines: a review
17. January 2017 Objectives The aim of this review was to map the currently available evidence on acceptability of oral paediatric medicines to aid in the selection of…
An evaluation of tools via patient-reported outcome measures to assess the acceptability of existing…
16. January 2017
Introduction
Palatability of liquid medicines is a recognised challenge within the paediatric population
Acceptability: “The overall ability of the patient and its caregiver to use the medicine as…
AGE RELATED BIORELEVANT DISSOLUTION TESTING FOR PAEDIATRIC FORMULATIONS
16. January 2017
INTRODUCTION
Dissolution of oral dosage forms depends on the GI tract physiological conditions, and definition of the dissolution profile in conditions that reflect the in vivo GI environment can lead…
A systematic review of the use of dosage form manipulation to obtain required doses to inform use of…
03. January 2017 Abstract This study sought to determine whether there is an evidence base for drug manipulation to obtain the required dose, a common feature of…
Accelerated oral nanomedicine discovery from miniaturized screening to clinical production…
27. October 2016 Considerable scope exists to vary the physical and chemical properties of nanoparticles, with subsequent impact on biological interactions; however, no…
Recommended strategies for the oral administration of paediatric medicines with food and drinks in…
11. October 2016 Objectives This review focuses on the recommended strategies for the oral administration of paediatric medicines with food in the context of their…