Since famotidine (FA) is prescribed for gastrointestinal diseases orodispersible tablets could contribute to patients’ compliance. Its bitter taste and poor compressibility pose formulation challenges which were addressed in this study.…

Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical…

Taste acceptability is an important factor in the development of a drug product, especially when it comes to paediatric dosage forms. Gustoceutics provides a biosensor taste testing service to improve acceptability and compliance of…

The aim of the current study is to develop and evaluate patient friendly taste masked anthelmintics chewable tablets for pediatrics and geriatrics use. However, the chewable tablets have to disintegrate in the mouth before swallowing, which…

Objective The aim of this study was to develop a paediatric oral preparation for ibuprofen. Significance Ibuprofen is widely used for defervescence in children, but medication compliance is poor due to its bitter taste. Dry…

The development of personalised paediatric dosage forms using 3D printing technologies has gained significant interest over the last few years. In the current study extruded filaments of the highly bitter Diphenhydramine Hydrochloride (DPH)…

Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor medication with a very bitter taste that plays an essential role in patient compliance in the oral dosing form. In this study, an attempt was made to mask the…

CycloLab Cyclodextrin R&D Laboratory, Ltd., Hungary and Daicel Corporation have jointly published a white paper on the bitterness masking effect of β-cyclodextrin (β-CD) in the formulation of orally disintegrating tablets (ODTs) using…

Masking the unpleasant taste of the pharmaceutically active ingredients plays a critical role in patient acceptance, particularly for children. This work’s primary objective was the preparation of taste-masked ibuprofen microparticles using…

A novel dry coating technique for fine particles that does not require any liquids has been developed. Swellable ordered-mixed drug particles (Swell-OM-spheres, SOS), using a modified starch as the core particle and a drug coating layer…