Parenteral excipients are substances used in the formulation of injectable drugs. They are an important component of parenteral products as they help to stabilize, solubilize, and enhance the delivery of active pharmaceutical ingredients (APIs) to the patient.
Pharma Excipients
Parenteral Excipients
Model-dependent pharmacokinetic analysis of enalapril following the administration of novel…
Despite the legislative initiatives by the regulatory European medical agency (EMA) and the United States Food and Drug Administration Authority (FDA), an approved drug with child-appropriate dosage formulations are still absent for many drugs for pediatric heart failure. The pediatric patients are…
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Phase inversion-based nanoemulsions of medium chain triglyceride as potential drug delivery system…
Lipid nanoemulsions are attractive drug delivery systems for lipophilic drugs.
To produce nanoemulsions with droplets of very small diameter (<100 nm), we investigated thermotropic phase transitions as an alternative to the standard procedure of high-pressure homogenization. Employing shock…
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Insights on the Formulation of Recombinant Proteins
Recombinant proteins are large and complex molecules, whose therapeutic activity highly depends on their structure.
Formulation of biopharmaceuticals aims at stabilizing protein conformation, promoting its efficacy, and preventing safety concerns, such as immunogenicity. Currently, the rational…
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Excipients for Parenteral Use
Discover BASF’s wide range of excipients for parenteral use meeting the highest quality standards as well as BASF’s unparalleled experience in quality and regulatory affairs.
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PDF Download: EXCIPIENTS FOR PARENTERAL USE
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Current Developments in Excipient Science – Implication of Quantitative Selection of Each…
Implication of Quantitative Selection of Each Excipient in Product Development
Excipients’ role in designing different dosage forms does not require any introduction. These are the additives that are added to the formulation along with pharmacologically active substance. The main purpose of adding…
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Enhancement of saquinavir absorption and accumulation through the formation of solid drug…
Nanotechnology is now considered a promising drug delivery method for orally administered hydrophobic drugs to their sites of action. The effect of nanodispersion on cellular transport and accumulation of saquinavir (SQV) was investigated.
Methods
The transport of five solid drug…
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Interested why Kollidon® 12 PF / Kollidon® 17 PF are particularly suitable for parenteral…
Did you know that Kollidon® 12 PF and Kollidon® 17 PF are highly suitable for injectable formulations?
Kollidon® 12 PF/ Kollidon® 17 PF low molecular weight make them particularly suitable for parenteral
applications. Additionally, they are used as matrix formers in solid dispersions, highly…
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Introduction to pharmaceutical excipients – a video
In this video Chris Moreton gives an interesting insight on pharmaceutical excipients.
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Parenteral nanosuspensions: a brief review from solubility enhancement to more novel and specific…
01. August 2018
Advancements in in silico techniques of lead molecule selection have resulted in the failure of around 70% of new chemical entities (NCEs). Some of these molecules are getting rejected at final developmental stage resulting in wastage of money and…
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Protein-excipient interactions evaluated via NMR studies in polysorbate based multi-dose protein…
12. June 2018
Preservatives are excipients essentially needed in pharmaceutical multi-dose formulations to prevent microbial growth. Among available substances, phenol is widely used for parenterals, however, it is known to interact with non-ionic surfactants like…
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