Parenteral excipients are substances used in the formulation of injectable drugs. They are an important component of parenteral products as they help to stabilize, solubilize, and enhance the delivery of active pharmaceutical ingredients (APIs) to the patient.
Pharma Excipients
Parenteral Excipients
Protein-excipient interactions evaluated via NMR studies in polysorbate based multi-dose protein…
12. June 2018
Preservatives are excipients essentially needed in pharmaceutical multi-dose formulations to prevent microbial growth. Among available substances, phenol is widely used for parenterals, however, it is known to interact with non-ionic surfactants like…
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Polyethylene Glycol (PEG) Exposure in Parenteral Therapies for the Pediatric Population
13. December 2017 INTRODUCTION Polyethylene glycol (PEG) is a chemically inert, amphiphilic polymer used as an excipient in many pharmaceuticals for decades, and as a conjugate with biologicals (ie, PEGylation) since 1990. To…
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A 30-Year History of PLG Applications in Parenteral Controlled Drug Release
26. July 2017 Poly(lactide-glycolide) has been used for drug-delivery applications because of its beneficial physicochemical properties, long safety record, and reliable commercial supply. The history of…
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Self-assembled Nanomaterials for Chemotherapeutic Applications
29. January 2017
Abstract
The self-assembly of short designed peptides into functional nanostructures is becoming a growing interest in a wide range of fields from optoelectronic devices to nanobiotechnology. In the medical field, self-assembled peptides have especially attracted…
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Implantable Drug-Eluting Devices: A Novel Approach to Patient Care
23. January 2017
Implantable Drug-Eluting Devices: A Novel Approach to Patient Care
Implantable drug-eluting devices (also referred to as implantable drug delivery systems) offer several unique advantages over conventional oral or parenteral drug delivery methods. For…
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Excipients Use in Parenteral and Lyophilized Formulation Development
17. January 2017 Excipients Use in Parenteral and Lyophilized Formulation Development Abstract Excipients are the integral part of pharmaceutical product development to achieve the desired product profile (stability…
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Excipients Use in Parenteral and Lyophilized Formulation Development
11. May 2016 Excipients Use in Parenteral and Lyophilized Formulation Development Excipients are the integral part of pharmaceutical product development to achieve the desired product profile (stability and efficacy). This…
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Excipients Use in Parenteral and Lyophilized Formulation Development
05. February 2016 Excipients are the integral part of pharmaceutical product development to achieve the desired product profile (stability and efficacy). This review deals with understanding of the physicochemical properties of…
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The central role of excipients in drug formulation
Active substances are rarely administered alone. For example, levothyroxine, a synthetic form of the thyroid hormone, indicated in the treatment of hypothyroidism, is administered at a very low dosage, ranging from 15 μg to 200 μg. These very small amounts of powder mean that it is not possible…
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Formulation and evaluation of pantaprazole transdermal patches for enhanced therapeutic efficacy
27. May 2015 M.R.Shivalingam*1,A.Vineela2, K.Vaishnavi1, Ch.Sunanda1, V.Abraham Prince1, S.Jyotsna31Department of Pharmaceutics, Victoria…
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