Pharma Excipients
Pellet
Controlled Drug Release from a non-soluble & pH stable pellet system based on a novel type of…
11. August 2017
Controlled Drug Release from a non-soluble & pH stable pellet system based on a novel type of mesoporous silica
The goal of this study was to test the feasibility to load non-ordered, non-spherical mesoporous silica with the model drug paracetamol, and…
Read More...
Read More...
UV imaging of multiple unit pellet system (MUPS) tablets: A case study of acetylsalicylic acid…
09. August 2017 Abstract The applicability of multispectral ultraviolet (UV) imaging in combination with multivariate image analysis was investigated to monitor API degradation within multiple unit pellet system (MUPS) tablets…
Read More...
Read More...
Tablets of multi-unit pellet system for controlled drug delivery
05. August 2017 Abstract The tablet of multi-unit pellet system (TMUPS), using coated pellets, for controlled release of drugs is an effective therapeutic alternative to conventional immediate-release dosage forms. The main…
Read More...
Read More...
Die wichtigsten Verfahren zur Pelletherstellung
11. July 2017
Klaus Möller - Glatt GmbH
Pellets sind die Tausendsassas unter den festen Darreichungsformen. Angesiedelt irgendwo zwischen Pulver und Granulat, machen sie bittere Medizin verträglich und befriedigen in phantasievollen Darreichungsformen, sogar den Spieltrieb von…
Read More...
Read More...
Dual-mechanism gastroretentive drug delivery system loaded with an amorphous solid dispersion…
Abstract
In the present study, we aimed to prepare a gastroretentive drug delivery system that would be both highly resistant to gastric emptying via multiple mechanisms and would also potentially induce in situ supersaturation. The bioadhesive floating pellets, loaded with an amorphous…
Read More...
Read More...
Mucoadhesive properties of thiolated pectin-based pellets prepared by extrusion-spheronization…
06. February 2017 Abstract The aim of this study was to develop mucoadhesive pellets on a thiolated pectin base using the extrusion-spheronization technique. Thiolation of pectin was performed by esterification with…
Read More...
Read More...
Multiple-unit tablet of probiotic bacteria for improved storage stability, acid tolerability, and in…
28. April 2016
Abstract: The aim of this study was to formulate probiotics-loaded pellets in a tablet form to improve storage stability, acid tolerability, and in vivo intestinal protective effect. Bacteria-loaded pellets primarily prepared with hydroxypropyl methylcellulose…
Read More...
Read More...
FORMULATION DEVELOPMENT AND STATISTICAL OPTIMIZATION OF IVABRADINE HYDROCHLORIDE FLOATING PULSATILE…
12. March 2016
Formulation Developement and Statistical Optimization of Ivabradine Hydrochloride Floating Pulsatile Pellets by Fluidized Bed Coating Technique
Objective: The objective of the current work was to develop Ivabradine hydrochloride (HCl) floating pulsatile…
Read More...
Read More...
Non Mcc Polymer as a Pelletisation Aid: A Review
20. February 2016
Extrusion spheronization is the widely used method by which the pellets are formulated. Pellets have certain advantages in the development of modified release dosage forms, Because of their regular shape and size they are suitable for coating and encapsulation…
Read More...
Read More...
Extended-release venlafaxine pellets: scaling up – Poster Ashland AAPS 2014
06. December 2015
Introduction:
This study from Ashland was undertaken to investigeate the influence of coating process scale when applying an organic solvent based modified release coating to multiparticulates using a Wurster process.
Download the full poster here…
Read More...
Read More...