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Polymers
Vitamin E-tocopheryl polyethylene glycol succinate decorated drug delivery system with synergistic…
To overcome cancer drug resistance and to reverse tumor immunosuppression, a vitamin E-tocopheryl polyethylene glycol succinate (TPGS) decorated polymer-based drug delivery system was developed. The effects of the drug delivery system on diverse proteins involved in cell apoptosis, cancer invasion,…
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Biocompatibility studies of polyurethane electrospun membranes based on arginine as chain extender
Electrospun polymers are an example of multi-functional biomaterials that improve the material-cellular interaction and aimed at enhancing wound healing. The main objective of this work is to fabricate electrospun polyurethane membranes using arginine as chain extender (PUUR) in order to test the…
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Big family of nano- and microscale drug delivery systems ranging from inorganic materials to…
Traditional drug administration routs suffer from low selective distribution, poor solubility, fast elimination and damaging adjacent healthy tissues (especially in cancer therapy). Thus, drug delivery systems (DDSs) which could deliver drug to target site have broadly been investigated to upsurge…
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Nanofibers in Drug Delivery System
The possible applications of electrospun fibers in drug delivery systems (DDS) are critically examined in this study. Nanofibers are among the most desirable resources in some kind of a variety of scenarios due to their operational capabilities including valuable features for another young…
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Polymers in Pharmaceutical Additive Manufacturing A Balancing Act Between Printability and Product…
Materials and manufacturing processes share a common purpose of enabling the pharmaceutical product to perform as intended. This review on the role of polymeric materials in additive manufacturing of oral dosage forms, focuses on the interface between the polymer and key stages of the additive…
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Impact of Drug–Polymer Intermolecular Interactions on Dissolution Performance of Copovidone-Based…
For poorly soluble drugs formulated as amorphous solid dispersions (ASDs), fast and complete release with the generation of drug-rich colloidal particles is beneficial for optimizing drug absorption. However, this ideal dissolution profile can only be achieved when the drug releases at the same…
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Polymers in Pharmaceutical Additive Manufacturing: A Balancing Act Between Printability and Product…
Materials and manufacturing processes share a common purpose of enabling the pharmaceutical product to perform as intended. This review on the role of polymeric materials in additive manufacturing of oral dosage forms, focuses on the interface between the polymer and key stages of the additive…
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Drug–Polymer Interactions in Acetaminophen/Hydroxypropylmethylcellulose Acetyl Succinate Amorphous…
The bioavailability of insoluble crystalline active pharmaceutical ingredients (APIs) can be enhanced by formulation as amorphous solid dispersions (ASDs). One of the key factors of ASD stabilization is the formation of drug–polymer interactions at the molecular level. Here, we used a range of…
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Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually…
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An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems
Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in vitro techniques frequently used for examining…
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