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Polyvinyl Alcohol – PVA
Fabrication of modified-release custom-designed ciprofloxacin tablets via fused deposition modeling…
Aim: The aim of the present work was to fabricate customized tablets of ciprofloxacin hydrochloride through 3D printing for optimized dosing.
Materials & methods: A hot melt extrusion technique was employed to produce polyvinyl alcohol filaments with differing strengths of ciprofloxacin…
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The Stabilizing Excipients in Dry State Therapeutic Phage Formulation
Phage therapy has gained prominence due to the increasing pathogenicity of “super bugs” and the rise of their multidrug resistance to conventional antibiotics. Dry state formulation of therapeutic phage is attractive to improve their “druggability” by increasing their shelf life, improving their…
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Solidification of SMEDDS by fluid bed granulation and manufacturing of fast drug release tablets
Solidification of self-microemulsifying drug delivery systems (SMEDDS) is a rising experimental field with important potential for pharmaceutical industry, however fluid-bed granulation with SMEDDS is yet an unexplored solidification technique. The aim of the study was to solidify carvedilol-loaded…
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Enhanced dissolution and oral bioavailability of poorly water-soluble herb (Kaempferia parviflora)…
Kaempferia parviflora (KP) is a Thai traditional herb. The primary pharmacologically active substances are methoxyflavones, namely, 5,7-dimethoxyflavone, 5,7,4′-trimethoxyflavone, and 3,5,7,3′,4′-pentamethoxyflavone. These methoxyflavones are poorly soluble in water and thus have low oral…
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Advanced Tablet Coating Development: Applying Optical Coherence Tomography (OCT) as a PAT Tool for…
Purpose: Novel tablet coating approaches include the development of continuous coating technologies. This requires a high level of automation to assure the quality and safety of the final coated product. Despite automation of control procedures also approaches of in-line process analytical…
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Polyvinyl Alcohol (PVA) for Tablet Coating Applications: Enhancing Formulation Flexibility
Purpose: Polyvinyl alcohol (PVA) is a well-established polymer for film coating. PVA is a synthetic, bio-compatible and toxicologically well characterized polymer. It is frequently used in pre-mixed coating formulations. Fixed combinations with additional ingredients are well established. By…
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Enhancement of saquinavir absorption and accumulation through the formation of solid drug…
Nanotechnology is now considered a promising drug delivery method for orally administered hydrophobic drugs to their sites of action. The effect of nanodispersion on cellular transport and accumulation of saquinavir (SQV) was investigated.
Methods
The transport of five solid drug…
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Application of 3D printing technology and quality by design approach for development of…
Pediatric population is a sensitive sector of the healthcare and pharmaceutical field with additional needs compared to the adult population. Extemporaneous formulations for children are generally prepared by manipulating adult formulations, but medication errors can result in suboptimal efficacy…
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Development and Evaluation of Fast Dissolving Oral Film of Losartan Potassium
23. February 2016
Fast dissolving oral film of Losartan potassium were prepared and evaluated with an objective to rapid dissolution of drug and absorption which may produce the rapid onset of action in the treatment of hypertension and provides the convenient means of …
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Design and Evaluation of Buccal Patch Containing Combination of Hydrochlorothiazide and Lisinopril
19. February 2016
Design and Evaluation of Buccal Patch Containing Combination of Hydrochlorothiazide and Lisinopril
Purpose: The objective of the present study was to formulate and evaluate buccal patches containing combination of lisinopril (LP) and hydrochlorothiazide (HCZ).…
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