Polyvinyl Alcohol – PVA

The increasing demand for innovative drugs and personalized treatment is radically changing the pharmaceutical industry, where significant efforts in research and development (R&D) are taking place. Three-dimensional (3D) printing offers interesting solutions for these demands, solving some of…
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This research work is to develop nanofiber loaded in -situ gel for the delivery of fenofibrate to the posterior ocular site. Fenofibrate had showed its efficacy in neovascular ocular diseases under clinical studies but its low aqueous solubility makes difficult to develop a suitable ocular…
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Abstract Purpose Amorphous solid dispersions (ASD) for nasal delivery offer the opportunity to increase drug release performance, while using polymers with mucoadhesive properties. The aim of the present study was to apply this solubility enhancement technique to a poorly soluble drug for nasal…
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Everolimus (RAD001) a mammalian target of rapamycin has been hampered by poor solubility, affecting its dissolution rate, a relationship that extends to low bioavailability. Nanoparticles (NP) based on Soluplus (SOL®) and Polyvinyl alcohol (PVA) was fabricated by electrospraying (ES) for the…
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Purpose Selective laser sintering (SLS) is promising for printing oral dosage forms. Print ranges for commonly used pharmaceutical polymers not yet established for additive manufactured medications. Evaluate dedicated polymers for pharmaceutical applications. Objectives…
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In the field of ocular drug delivery, topical delivery remains the most common treatment option for managing anterior segment diseases, while intraocular injections are the current gold standard treatment option for treating posterior segment diseases. Nonetheless, topical eye drops are associated…
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The development of wound-dressing materials has attracted significant research interests in recent years. With the advancement of nanofabrication, the application of nanoparticles (NPs) in drug delivery systems has become feasible. However, most existing work focuses on incorporation of metal,…
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Abstract The fabrication of an effective in situ gelling ophthalmic drug delivery vehicle is recently received enormous interest to overcome the demerits of conventional ocular solutions and achieve desired therapeutic efficacy. Poloxamer 407 and poloxamer 188 are among the most commonly used…
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Protecting moisture sensitive substances from environmental moisture is one of the biggest challenges in the pharmaceutical and nutritional supplements industry. Coating the tablet core with a suitable film coating therefore plays an important role in achieving a sufficient moisture barrier. It…
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Oral administration is the most commonly used form of treatment due to its advantages, including high patient compliance, convenient administration, and minimal preparation required. However, the traditional preparation process of oral solid preparation has many defects. Although continuous…
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