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Kolliphor® HS 15

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Description

The potent nonionic solubilizer.

Kolliphor® HS 15 is a potent non-ionic solubilizer and emulsifying agent, with low toxicity. Ideal for solubilizing low-solubility actives in microemulsions, it helps tackle even the toughest solubilization challenges. It is used for manufacturing aqueous parenteral preparations with vitamins A, D, E and K, plus lipophilic APIs such as propanidid, miconazole, alfadolone, alfaxalone, nifedipine, and piroxicam. Kolliphor® HS 15 is soluble in water, ethanol, and 2-propanol. As a solubilizer, it is particularly suitable for parenteral and oral dosage forms, and lends itself well to veterinary formulations.

  • Low histamine release, reduces side-effects
  • Thermal stability, suitable for sterilization
  • Lower hemolytic activity compared to other polyoxyethylene-based surfactants
  • Monographed in Ph. Eur. and USP-NF

Additional information

Manufacturer

BASF

Quality

Ph.Eur., USP/NF

Cas-No

70142-34-6

Function

Nonionic solubilizer and emulsifier (surfactant; HLB = 15), Redispersing agent

Composition

Macrogol 15 hydroxystearate, Polyethoxylated 12-hydroxystearic acid, Polyoxyl 15 hydroxystearate

Documents and Links

Safety Data Sheet

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