Mesoporous Silica: for solubility enhancement of challenging compounds
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Silica
Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo…
21. March 2016
The aim of the present study was to prepare sublingual delivery systems for sildenafil and evaluate its relative bioavailability after sublingual administration in rabbits to attain a rapid onset of action with good efficacy at lower doses. For sublingual application,…
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Increasing Drug Solubility with Solid Dispersions of SilSol 6035 Silica Formulated Into Sublingual…
04. March 2016
Improving the solubility of BCS class 2 drugs is a continuing challenge for the pharmaceutical formulator. Improving solubility could allow for formulations using significantly less active and open the door to new dosage forms and avenues for lifecycle extensions. Creating…
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Grace Syloid Silica Gels & Mesoporous Silica in the field of Drug Delivery
13. November 2015
Grace Syloid Silica Gels & Mesoporous Silica in the field of Drug Delivery
Friday, November 27, 2015 at Safran Zunft in Basel
10.00 Morning session organized by IMPAG
Registration for morning session by IMPAG
12.15 PharmaLunch…
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Syloid® XDP silica – New Application Note on Solid delivery of PEG drug solubilizers –…
22. September 2015
Syloid® XDP silica: Carrier for liquid drug solubilizers in solid dosage form.
The solubility of poorly soluble drugs can be increased by using solubilizers such as polyethylene glycols (PEG), Tween 80 etc. These solublizers can be used to increase oral bioavailability…
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Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite® – Abstract
In vitro drug release from well-defined particle-size fractions of the mesoporous magnesium carbonate material Upsalite(®) was investigated in detail using ibuprofen, a biopharmaceutics classification system class II drug, as the model compound. The weight of loaded drug corresponded to 30% of the…
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Exploring the potential of porous silicas as a carrier system for dissolution rate enhancement of…
22. June 2016
Abstract
Malaria is a parasitic and vector determined blood-conceived infectious disease transmitted through infected mosquitoes. Anti-malarial drug resistance is a major health problem, which hinders the control of malaria. Drug-resistant malaria when surveyed, the…
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Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel
WORMS, GERMANY – May 26, 2015 – W. R. Grace & Co. (NYSE: GRA) announces that its manufacturing facility in Worms, Germany has received good manufacturing practice (GMP) certification from EXCiPACT™, an independent organization that certifies manufacturers, suppliers, and distributors of…
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SYLOID® FP SILICAS – Multifunctional Additives for Better Stability of Botanical
Main Formulation Challenges
The natural product market has experienced tremendous growth in recent years. Botanicals and probiotics are growing
more popular today as people seek out natural remedies to health conditions. Probiotics are “live” organisms, from the
formulations perspective key…
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