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Solution
What is ideal solubility?
An explanatory video by Prof. Simon Gaisford – Pharma Drama
Welcome to Pharma Drama, the channel where we look at the science of healthcare and healthcare products. In this video I’m going to explain the concept of ideal solubility – so if that sounds ideal, get yourself a drink and then…
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Hayashibara Trehalose SG – For Culture Media Use brochure
Hayashibara ― A world leading supplier of pharmaceutical grade Trehalose
Founded as a starch syrup manufacturer in 1883, Hayashibara has grown into a company with strong research and development expertise, engaging in original and creative research. Utilizing our technological background in…
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Topically applied lipid-containing emulsions based on PEGylated emulsifiers: Formulation,…
PEGylated emulsifiers have been largely used in topical formulations for skin research. They have been a continuous study focus in our group as well. According to our previous studies, severe interruptions of the skin barrier were observed with certain types of emulsifiers. To restore the skin…
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Advanced Formulations/Drug Delivery Systems for Subcutaneous Delivery of Protein-Based…
Multiple advanced formulations and drug delivery systems (DDSs) have been developed to deliver protein-based biotherapeutics via the subcutaneous (SC) route. These formulations/DDSs include high-concentration solution, co-formulation of two or more proteins, large volume injection, protein…
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Sequential fixed-fluidized bed foam granulation (SFFBFG) and drying: Multivariate model development…
Foam granulation (FG) is a non-conventional technique in which a binding solution is sprayed as aqueous foam. The main objectives of this work are, converting a lab-scale fluidized bed dryer into a fluidized bed foam granulator and dryer. Second, developing a partial least squares regression model…
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Dissolution Behavior of Weakly Basic Pharmaceuticals from Amorphous Dispersions Stabilized by a…
Amorphous solid dispersions (ASDs) are a well-documented formulation approach to improve the rate and extent of dissolution for hydrophobic pharmaceuticals. However, weakly basic compounds can complicate standard approaches to ASDs due to pH-dependent solubility, resulting in uncontrolled drug…
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Production, physicochemical investigations, antioxidant effect, and cellular uptake in Caco-2 cells…
The purpose of this study was to develop astaxanthin (AST)-loaded self-microemulsifying drug delivery system (SMEDDS) tablets and evaluate their physicochemical and biological properties. The optimized liquid (L)-AST SMEDDS formulation was composed of rice bran oil (33.67%), Kolliphor® RH 40…
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Superporous poly(β-Cyclodextrin) cryogels as promising materials for simultaneous delivery of both…
Here, one step, simple preparation of superporous p(β-cyclodextrin) (p(β-CD)) cryogels in the presence of various ratios of crosslinker, divinyl sulfone (DVS) e.g., 100, 150, 200% mole with respect to the mole ratio of 6 hydroxyl groups on β-CD unit under cryogenic conditions were reported for the…
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Novel Technique for Coating of Fine Particles Using Fluidized Bed and Aerosol Atomizer
Fine particles are widely used in many industrial fields, and there are many techniques applied for these particles, like electroplating, and chemical and physical vapor deposition. However, in the food and pharmaceutical industries, most coating processes conducted with fluidized bed use core…
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Development of a stable oral pediatric solution of hydrochlorothiazide by the combined use of…
Hydrochlorothiazide (HCT) is widely used in pediatrics for hypertension management. Due to the lack of pediatric commercial forms, community or hospital pharmacies generally prepare HCT extemporaneous pediatric suspensions by dispersing in water a portion of a crushed tablet or the drug powder;…
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