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European Paediatric Formulation Initiative workshop report: Improving the administration of oral…
Accurate dosing of the right medicine to the right patient is a key element of safe and efficacious pharmacotherapy, yet prone to technical challenges and human error when dosing involves the administration of small volumes of liquid medicines. For this reason, the topic has gained increased…
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Pediatric Oral Formulations: An Updated Review of Commercially Available Pediatric Oral Formulations…
Oral pediatric formulations are either ready-to-use or require manipulation, and multi-use or single-use. Strong encouragement for preservative-free pediatric formulations has resulted in fewer multi-use solutions or suspensions in favor of single-use solid oral dosage forms. This updated review…
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Stabilization of Glucagon by Trehalose Glycopolymer Nanogels
23. January 2018
Abstract
Glucagon is a peptide hormone used for the treatment of hypoglycemia; however, its clinical potential is limited by its insolubility and instability in solution. Herein, the encapsulation, stabilization, and release of glucagon by trehalose glycopolymer…
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Bilateral Effects of Excipients on Protein Stability: Preferential Interaction Type of Excipient and…
16. April 2017
Purpose
Understanding the mechanism of protein-excipient interaction and illuminating the influencing factors on protein stability are key steps in the rational design of protein formulations. The objective of this study was to assess effects of preferential…
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Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System…
31. March 2016
The objective was to assess the impact of larger than conventional amounts of 14 commonly used excipients on Biopharmaceutics Classification System (BCS) class 3 drug absorption in humans. Cimetidine and acyclovir were used as model class 3 drugs across three separate…
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Roquette Freres receives EXCiPACT certification
08. March 2016
Roquette Freres' plant in Lestrem, France, has earned EXCiPACT certification for Good Manufacturing Practice (GMP) from SGS France, one of EXCIPACT’s internationally-recognised certification bodies. The certificate covers the design, production and storage of…
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Capsugel Advances the First Intrinsically Enteric Capsule Technology
Capsugel is a global leader in delivering high-quality, innovative dosage forms and solutions to its customers in the health care industry. The company’s Hard Capsule business unit offers customers the broadest portfolio of gelatin, vegetarian and other specialized capsule…
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