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Spray drying
Nano-and Microfabrication Techniques in Drug Delivery – Part 1
Nano-and Microfabrication Techniques in Drug Delivery
See the new book, edited by Dimitrios Lamprou. It brings together technical, clinical, regulatory and industrial perspectives. It provides future prospective and includes the potential clinical applications of nano/microfabrication technologies.…
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Soluplus as a solubilizing excipient for poorly water-soluble drugs: Recent advances in formulation…
Since the emergence of Soluplus® (SOL) as a commercial graft copolymer, multiple publications have been issued on its promising potential as a solubilizing excipient that could promote the dissolution rate and bioavailability of several poorly water-soluble drugs. Numerous drug formulation…
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Development and Characterization of Chitosan-Based-Spray-Dried Solid Dispersions of Apigenin: 3D…
This study aimed to develop chitosan-based apigenin spray dried solid dispersion using 1:1,1:1.5,1:2 w/w ratios. The results of process yield and drug assay were found to be (87.5%, 94.2%, and 95.86%), (95.2 ±1.34%), (99.5 ±0.85%), and (97.6 ±2.42%), respectively, for AC1, AC2, and AC3. Flow…
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F-MELT: The Cost-Effective Solution For Producing High-Quality Orally Disintegrating Tablets (ODTs)
See the sixth issue of Fuji Chemical Industries Technical Newsletter:
Directly compressible excipient system for fast-Disintegrating oral tablets*,
F-MELT® formulations are designed with a focus on three important characteristics of ODTs: tablet hardness, mouthfeel, and acceptable oral…
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Impact of matrices composition and processes on β-galactosidase encapsulation
Advances in existing drying techniques are essential for upgrading large scale industries. Enzymes are often degraded by drying processes. Spray drying (SD) has detrimental effects on bioactive molecules at high temperatures. Freeze-drying (FD) is a reference technique capable of drying sensible…
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Impact of Different Saccharides on the In-Process Stability of a Protein Drug During Evaporative…
Objectives
Solid biopharmaceutical products can circumvent lower temperature storage and transport and increase remote access with lower carbon emissions and energy consumption. Saccharides are known stabilizers in a solid protein produced via lyophilization and spray drying (SD). Thus, it is…
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A ready-to-use dry powder formulation based on protamine nanocarriers for pulmonary drug delivery
The use of oral antibiotic therapy for the treatment of respiratory diseases such as tuberculosis has promoted the appearance of side effects as well as resistance to these treatments. The low solubility, high metabolism, and degradation of drugs such as rifabutin, have led to the use of combined…
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Inhalable Microparticles Embedding Biocompatible Magnetic Iron-Doped Hydroxyapatite Nanoparticles
Recently, there has been increasing interest in developing biocompatible inhalable nanoparticle formulations, as they have enormous potential for treating and diagnosing lung disease. In this respect, here, we have studied superparamagnetic iron-doped calcium phosphate (in the form of…
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Spray drying and nano spray drying as manufacturing methods of drug-loaded polymeric particles
In this review, benefits and drawbacks of the process of spray drying and nano spray drying with regard to the manufacturing of polymeric particles for pharmaceutical applications are discussed. Spray drying has been used for many years in the food, chemical and pharmaceutical industries for…
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Co-processed Hydroxypropyl Methylcellulose – Mannitol as a Directly Compressible Excipient for…
Introduction
Controlled release dosage forms deliver an effective dose of the active pharmaceutical ingredient over a prolonged duration, which is particularly advantageous to maintain a constant plasma drug concentration within the therapeutic window. This effectively overcomes the negative…
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