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Stabilizer
Stability of APIs in Super Refined PEG – Maximise the Performance of Your Active…
Discover the Benefits of Super Refined Excipients
Polyethylene glycols (PEGs) are excipients that are widely used in oral, parenteral and topical delivery dosage forms. Low molecular weight PEGs, such as PEG 300 and PEG 400 in particular, are used as solvents in concentrated formulations that are…
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Towards the development of a biorelevant in vitro method for the prediction of nanoemulsion…
Ophthalmic oil-in-water nanoemulsions (NEs) are a complex technological platform, representing an advancement in the treatment of dry eye disease. In addition to enabling the incorporation of poorly soluble active pharmaceutical ingredients (APIs), NEs provide prolonged residence time of APIs and…
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who advances drug delivery? we do. – pharmaceutical product and solution guide by Ashland
advancing drug delivery
Ashland’s pharmaceutical team prides itself on advancing drug delivery with sophisticated science-based solutions. Our global centers of excellence contain the latest equipment and our research scientists and formulators are ready to work with you from concept to…
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Transform Your Brick-Dust API into an Effective oral Drug Candidate with Apinovex Polymers
Lubrizol Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel excipient has a broad API and solvent compatibility to produce Amorphous Solid Dispersions (ASD) of your brick-dust API.
1. Unlock the Potential Of…
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Investigation of In Vivo Bioavailability Enhancement of Iloperidone-Loaded Solid…
Purpose
The current research focuses on enhancement of in vitro dissolution and in vivo bioavailability characteristics of iloperidone (IP) by formulation, optimization of L-SNEDDS using Box-Behnken design (BBD), and desirability function. L-SNEDDS were transformed into free-flowing powders by…
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Thermodynamic Mechanism of Physical Stability of Amorphous Pharmaceutical Formulations
Hygroscopicity is an important factor affecting the physical stability of amorphous solid dispersions (ASDs) during long-term storage. In this work, the effects of temperature, relative humidity (RH), and polymeric excipients on the phase behavior of amorphous irbesartan (IRB) and oxaprozin (OXA)…
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The Power of Excipient Purity in API Stability – Maximise the Performance of Your Active…
Discover the Benefits of Super Refined Excipients
Active Pharmaceutical Ingredient (API) stability is one of the most important factors in pharmaceutical formulation development. Degradation and instability are common problems that can lead to extended development timescales, additional…
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Innovative lipids for Your Nucleic Acid Delivery research
The history and evolution of Nucleic Acid Delivery systems
mRNA and liposomes were both first discovered in the 1960s, and liposomes were used to deliver mRNA into eukaryotic cells in 1978.1,2 Even with the ability to inject mRNA into cells, there were several technical challenges to overcome…
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Co-Crystallization Approach to Enhance the Stability of Moisture-Sensitive Drugs
Stability is an essential quality attribute of any pharmaceutical formulation. Poor stability can change the color and physical appearance of a drug, directly impacting the patient’s perception. Unstable drug products may also face loss of active pharmaceutical ingredients (APIs) and degradation,…
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Advances in Formulation and Manufacturing Strategies for the Delivery of Therapeutic Proteins and…
Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug molecules due to their high specificity to the site of action and reduced adverse effects resulting in increased use of these agents for medical treatments and therapies. Consequently, there is a need to formulate…
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