Browsing Category
Stabilizer
Fabrication and evaluation of stable amorphous polymer-drug composite particles via a nozzle-free…
Abstract
We present a promising method for producing amorphous drug particles using a nozzle-free ultrasonic nebulizer with polymers, specifically polyvinylpyrrolidone (PVP), poly(acrylic acid) (PAA), and Eudragit® S 100 (EUD). Model crystalline phase drugs–Empagliflozin, Furosemide, and…
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Lipid-based nanoparticles as a promising treatment for the skin cancer
Abstract
The prevalence of skin disorders, especially cancer, is increasing worldwide. Several factors are involved in causing skin cancer, but ultraviolet (UV) light, including sunlight and tanning beds, are considered the leading cause. Different methods such as chemotherapy, radiotherapy,…
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New Excipient For Oral Drug Delivery: CNC Derived From Sugarcane Bagasse-Derived Microcrystalline…
Abstract
Nanocrystalline cellulose (CNC) has emerged as a subject of researcher’s interest because of its diverse attributes encompassing biocompatibility, sustainability, a high aspect ratio, and an abundance of −OH groups suitable for modifications. Sugarcane bagasse microcrystalline cellulose…
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Formulation development, in-vitro and ex-vivo evaluation of dry adsorbed solid lipid nanoparticles:…
Abstract
Aim: The present study was aimed at preparing stable dry adsorbed nanoparticles (DANs) of olanzapine (OLZ) loaded solid lipid nanoparticles (SLNs) for sustained release.
Materials/methods: OLZ SLNs were prepared by hot melt emulsification and ultrasonication using Precirol ATO 5 (PRE)…
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SEPPIC Introduces SEPINEO P 600 Polymer for Topical Application
SEPINEO™ P 600 is multifunctional: thickening, emulsifying, stabilizing and texturing agent. Acrylamide/Sodium Acryloyldimethyl Taurate Copolymer/Isohexadecane & Polysorbate 80. Ready-to-use, it is designed for the formulation such as gels and creams and is very easy to implement.
SEPINEO™ P…
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BIOHALE® – Products for the Stabilization of Biologics
BioHale® is DFE Pharma´s, high-purity, low-endotoxin product portfolio for the stabilization of biologics. Because stability matters.
BioHale® Key promises:
Uncompromised quality
Security of supply
Expert support
Uncompromised quality
BioHale® high purity and low endotoxin…
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The dawning era of oral thin films for nutraceutical delivery: From laboratory to clinic
Abstract
Oral thin films (OTFs) are innovative dosage forms that have gained tremendous attention for the delivery of nutraceuticals. They are ultra-thin, flexible sheets that can be easily placed on the tongue, sublingual or buccal mucosa (inner lining of the cheek). These thin films possess…
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Topical pickering emulsion versus classical excipients: A study of the residual film on the human…
Abstract
The interest in Pickering emulsions is based on the possibility of replacing classical emulsifiers with solid particles. These emulsions are very attractive in the pharmaceutical field for their stability virtues and as a vehicle to deliver active ingredients. The study aimed to analyze…
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Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in…
Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities. KLEPTOSE® HPβCD (hydroxypropyl beta-cyclodextrin) has functioned as a stable…
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Development of a stability indicating high-performance liquid chromatography method for…
Abstract
This study presents a stability indicating high-performance liquid chromatography HPLC method for the determination of cenobamate (CNB) in presence of its main impurity (CNB H-impurity) and degradation products. The chromatographic separation was carried out on a Thermo BDS Hypersil-C18…
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