Biogrund

Abstract A threat to human health in developed and, in particular, in developing countries, counterfeit medicines represent the largest identified fraud market worldwide. 3D screen printing (3DSP), an additive manufacturing technology that enables large-scale production, offers unique opportunities…
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What were the reasons for developing a new disintegrant premix based on natural ingredients? For years, we have seen an increased interest in a healthy lifestyle on the consumer side. Not only in the USA, but also in Europe, consumers increasingly want to avoid chemical or synthetic ingredients and…
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This study aimed to develop a novel pH-modified nanoparticle with improved solubility and oral bioavailability of poorly water-soluble celecoxib by modifying the microenvironmental pH. After assessing the impact of hydrophilic polymers, surfactants and alkaline pH modifiers on the drug solubility,…
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This year Vitafoods Europe opens its doors for the last time in Geneva at Palexpo. From 14th to 16th May you can have a face-to-face chat with visitors and exhibitors again. Pharma Excipients gives you an overview of the excipient suppliers, their booths, main topics and products in the…
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Evaluation of a new disintegrant mixture from natural resources Introduction Tablet disintegration is most often required to divide a tablet into suitably small sub-units that facilitate achievement of the desired drug dissolution rate. While semi-synthetic or synthetic super-disintegrants are…
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Functional film coatings are a topic which considers many formulators. Therefore we gladly share this interesting overview by BIOGRUND. Definition of “Functional Film Coating”: A functional film coating has an influence on the drug release and is used to modify the release of the active…
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This year CPHI Europe opens its doors in Barcelona at Fira Barcelona Gran Via. From 24th to 26th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE and BioProduction will be held together with CPHI. Pharma Excipients gives you an…
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Protecting moisture sensitive substances from environmental moisture is one of the biggest challenges in the pharmaceutical and nutritional supplements industry. Coating the tablet core with a suitable film coating therefore plays an important role in achieving a sufficient moisture barrier. It…
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Hypromellose, a widely used polymer in the pharmaceutical industry, is available in several grades, depending on the percentage of substitution of the methoxyl and hydroxypropyl groups and molecular weight, and in various functional forms (e.g., suitable for direct compression tableting). These…
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Abstract This study aimed to prototype oral dental films (ODFs) loaded with diclofenac sodium (DS) using two different grades of CompactCel® polymers through a semi-solid extrusion (SSE) bioprinter. This three-dimensional (3D) printed ODFs were developed for the treatment of toothaches with…
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